MO Larsen, B Rolin, M Wilken, RD Carr, CF … - Diabetes, 2003 - Am Diabetes Assoc Knowledge about β-cell mass and/or function could be of importance for the
early diagnosis and treatment of diabetes. However, measurement of β-cell
function as an estimate of β-cell mass is currently the only method ... Cited by 31 - Related articles - BL Direct - All 5 versions
MO Larsen, CF Gotfredsen, M Wilken, RD Carr, … - Diabetologia, 2003 - Springer Aims/hypothesis. Type 2 diabetes is associated with impaired insulin action and
secretion, including dis- turbed pulsatile release. Impaired pulsatility has
been related to impaired insulin action, thus providing a possible link ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org LL Kjems, BM Kirby, EM Welsh, JD Veldhuis, M … - Diabetes, 2001 - Am Diabetes Assoc Most insulin is secreted in discrete pulses at an interval of ∼6 min.
Increased insulin secretion after meal ingestion is achieved through the
mechanism of amplification of the burst mass. Conversely, in type 2 ... Cited by 74 - Related articles - BL Direct - All 6 versions
M Larsen, M Elander, J Sturis, M Wilken, R … - Diabetologia, 2002 - Springer Aims/hypothesis. Pulsatile secretion is important for insulin action and
suitable animal models are impor- tant tools for examining the role of impaired
pulsatile insulin secretion as a possible link between beta-cell mass, ... Cited by 8 - Related articles - BL Direct - All 4 versions
M Tominaga, H Maruyama, G Bolli, JH … - Endocrinology, 1986 - Endocrine Soc To determine if the loss of the glucagon response to glucopenia that follows
destruction of beta cells is at least in part a consequence of the absence of
the normal glucopenia-induced decline in insulin secretion, pancreata from ... Cited by 9 - Related articles - All 3 versions
- ►diabetesjournals.org A Moore, S Bonner-Weir, R Weissleder - Diabetes, 2001 - Am Diabetes Assoc Pancreatic β-cell mass (BCM) is a major determinant of the quantity of insulin
that can be secreted. BCM is markedly reduced in type 1 diabetes because of
selective autoimmune destruction of β-cells. Accurate assessment of BCM in ... Cited by 55 - Related articles - BL Direct - All 4 versions
PB Clark, HD Gage, C Brown-Proctor, N … - European Journal of Nuclear Medicine and Molecular …, 2004 - Springer Abstract. The pancreas is one of the most heavily inner- vated peripheral organs
in the body. Parasympathetic and sympathetic neurons terminate in the pancreas
and pro- vide tight control of endocrine and exocrine functions. The aim of ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►physiology.org MO Larsen, CB Juhl, N Porksen, CF Gotfredsen … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Herein, we bridge -cell function and morphology in minipigs. We hypothesized
that different aspects of -cell dysfunction are present in obesity and obesity
with reduced -cell mass by using pulsatile insulin secretion as an early ... Cited by 13 - Related articles - All 4 versions
L Ladri re, F Malaisse-Lagae, R Alejandro, … - Cell Biochemistry and Function, 2001 - 万方数据资源系统 The possible use of a mouse monoclonal antibody directed against rat pancreatic
B-cell surface ganglioside(s) and labelled with radioactive iodine for selective
imaging of the endocrine pancreas by a non-invasive procedure was ... Cited by 13 - Related articles - BL Direct - All 2 versions
