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Scholar Results 1 - 10 of about 101 related to Buteau: Glucagon-like peptide 1 induces pancreatic β-cell proliferation via transactivation.... (0.09 sec) 

Glucagon-like peptide 1 induces pancreatic β-cell proliferation via transactivation of the …

- diabetesjournals.org
J Buteau, S Foisy, E Joly, M Prentki - Diabetes, 2003 - Am Diabetes Assoc
We previously provided evidence that glucagon-like peptide 1 (GLP-1) induces
pancreatic ß-cell growth nonadditively with glucose in a phosphatidylinositol
(PI) 3-kinase- and protein kinase C -dependent manner. However, the exact ...
Cited by 147 - Related articles - BL Direct - All 5 versions

Protein kinase Cζ activation mediates glucagon-like peptide-1–induced pancreatic β-cell …


J Buteau, S Foisy, CJ Rhodes, L Carpenter, TJ … - Diabetes, 2001 - Am Diabetes Assoc
Glucagon-like peptide-1 (GLP-1), an insulinotropic and glucoincretin hormone, is
a potentially important therapeutic agent in the treatment of diabetes. We
previously provided evidence that GLP-1 induces pancreatic β-cell growth ...
Cited by 138 - Related articles - BL Direct - All 4 versions

Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase …


J Buteau, R Roduit, S Susini, M Prentki - Diabetologia, 1999 - Springer
Glucagon-like peptide-1-(7±36)amide (GLP-1) is se- creted by the
enteroendocrine L-cells in response to fat meals and carbohydrates [1, 2]. It is
a potent glu- coincretin hormone which acts as a competence fac- tor in ...
Cited by 236 - Related articles - BL Direct - All 4 versions

Glucagon-like peptide-1 receptor signaling modulates β cell apoptosis


Y Li, T Hansotia, B Yusta, F Ris, PA Halban, … - Journal of Biological Chemistry, 2003 - ASBMB
Glucagon-like peptide-1 (GLP-1) stimulates insulin secretion and augments β
cell mass via activation of β cell proliferation and islet neogenesis. We
examined whether GLP-1 receptor signaling modifies the cellular ...
Cited by 254 - Related articles - BL Direct - All 7 versions

Exendin-4 Differentiation of a Human Pancreatic Duct Cell Line Into Endocrine Cells: …


J Zhou, MA Pineyro, X Wang, ME Doyle, JM … - Journal of cellular physiology, 2002 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 63 - Related articles - BL Direct - All 3 versions

Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5'- …

- endojournals.org
H Hui, A Nourparvar, X Zhao, R Perfetti - Endocrinology, 2003 - Endocrine Soc
The activation of the glucagon-like peptide-1 (GLP-1) receptor has been shown to
have an important role in the functional activity of islet ß-cells and in the
expansion of the islet cell mass. Constant remodeling of islet cell mass is ...
Cited by 145 - Related articles - BL Direct - All 4 versions

Antagonism of Rat {beta}-Cell Voltage-dependent K+ Currents by Exendin 4 Requires Dual …

- jbc.org
PE MacDonald, X Wang, F Xia, W El-kholy, … - Journal of Biological Chemistry, 2003 - ASBMB
Antagonism of voltage-dependent K + (Kv) currents in pancreatic -cells may
contribute to the ability of glucagon-like peptide-1 (GLP-1) to stimulate
insulin secretion. The mechanism and signaling pathway regulating these ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Glucagon-like peptide-1 prevents beta cell glucolipotoxicity


J Buteau, W El-Assaad, CJ Rhodes, L … - Diabetologia, 2004 - Springer
Aims/hypothesis. We have provided evidence that gluca- gon-like peptide-1, a
potential therapeutic agent in the treatment of diabetes, activates
phosphatidylinositol-3 kinase/protein kinase B signalling in the pancreatic ...
Cited by 113 - Related articles - BL Direct - All 4 versions

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic …

- endojournals.org
L Farilla, H Hui, C Bertolotto, E Kang, A Bulotta … - Endocrinology, 2002 - Endocrine Soc
A constant remodeling of islet cell mass mediated by proliferative and apoptotic
stimuli ensures a dynamic response to a changing demand for insulin. In this
study, we investigated the effect of glucagon-like peptide-1 (GLP-1) in ...
Cited by 193 - Related articles - BL Direct - All 6 versions

Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cell …


J Buteau, ML Spatz, D Accili - Diabetes, 2006 - Am Diabetes Assoc
The glucoincretin hormone glucagon-like peptide-1 (GLP-1) increases pancreatic
β-cell proliferation and survival through sequential activation of the
epidermal growth factor receptor (EGFR), phosphatidylinositol-3 kinase (PI ...
Cited by 49 - Related articles - BL Direct - All 4 versions


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