- ►diabetesjournals.org R Halse, LGD Fryer, JG McCormack, D … - Diabetes, 2003 - Am Diabetes Assoc We report here use of human myoblasts in culture to study the relationships
between cellular glycogen concentrations and the activities of glycogen synthase
(GS) and AMP-activated protein kinase (AMPK). Incubation of cells for 2 h ... Cited by 50 - Related articles - BL Direct - All 5 versions
JFP Wojtaszewski, SB Jørgensen, Y Hellsten, … - Diabetes, 2002 - Am Diabetes Assoc 5′-AMP-activated protein kinase (AMPK) functions as a metabolic switch in
mammalian cells and can be artificially activated by
5-aminoimidazole-4-carboxamide (AICA)-riboside. AMPK activation during ... Cited by 133 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org WG Aschenbach, MF Hirshman, N Fujii, K … - Diabetes, 2002 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is proposed to stimulate fat and
carbohydrate catabolism to maintain cellular energy status. Recent studies
demonstrate that pharmacologic activation of AMPK and mutations in the ... Cited by 52 - Related articles - BL Direct - All 5 versions
- ►physiology.org GS Olsen, BF Hansen - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc We examined whether acute activation of 5'-AMP-activated protein kinase (AMPK)
by 5'-aminoimidazole-4-carboxamide-1- -D-ribonucleoside (AICAR) ameliorates
insulin resistance in isolated rat skeletal muscle. Insulin resistance was ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►physiology.org SL Longnus, RB Wambolt, HL Parsons, RW … - … Journal of Physiology- Regulatory, Integrative and …, 2003 - Am Physiological Soc We tested the hypothesis that activation of AMP-activated protein kinase (AMPK)
promotes myocardial glycogenolysis by decreasing glycogen synthase (GS) and/or
increasing glycogen phosphorylase (GP) activities. Isolated working hearts ... Cited by 54 - Related articles - BL Direct - All 3 versions
R Halse, SM Bonavaud, JL Armstrong, JG … - Diabetes, 2001 - Am Diabetes Assoc A key feature of type 2 diabetes is impairment in the stimulation of glycogen
synthesis in skeletal muscle by insulin. Glycogen synthesis and the activity of
the enzyme glycogen synthase (GS) have been studied in human myoblasts in ... Cited by 21 - Related articles - BL Direct - All 5 versions
D Carling, DG Hardie - Biochimica et biophysica acta, 1989 - ncbi.nlm.nih.gov In addition to acetyl-CoA carboxylase and HMG-CoA reductase, the AMP-activated
protein kinase phosphorylates glycogen synthase, phosphorylase kinase,
hormone-sensitive lipase and casein. A number of other substrates for the ... Cited by 140 - Related articles - All 3 versions
SB Jørgensen, JN Nielsen, JB Birk, GS Olsen, … - Diabetes, 2004 - Am Diabetes Assoc The 5'AMP-activated protein kinase (AMPK) is a potential antidiabetic drug
target. Here we show that the pharmacological activation of AMPK by
5-aminoimidazole-1-ß-4-carboxamide ribofuranoside (AICAR) leads to ... Cited by 63 - Related articles - BL Direct - All 4 versions
ER Hudson, DA Pan, J James, JM Lucocq, SA … - Current biology, 2003 - Elsevier The AMP-activated protein kinase (AMPK) is an αβγ heterotrimer that is
activated by low cellular energy status and affects a switch away from
energy-requiring processes and toward catabolism [1]. While it is primarily ... Cited by 146 - Related articles - All 10 versions
S Baqué, JJ Guinovart, JC Ferrer - FEBS letters, 1997 - Elsevier We have studied the intracellular localization of glycogenin by fusing green
fluorescent protein (GFP) to the N-terminus of rabbit muscle glycogenin and
expressing the chimeric protein in C 2 C 12 , COS-1 and rat hepatic cells. ... Cited by 17 - Related articles - All 5 versions
