Z Ling, M Van de Casteele, J Dong, H … - Diabetes, 2003 - Am Diabetes Assoc We previously reported that interleukin-1β (IL-1β) alone does not cause
apoptosis of β-cells, whereas when combined with γ-interferon (IFN-γ) and
tumor necrosis factor-α (TNF-α), it exerts a distinct apoptotic effect. ... Cited by 14 - Related articles - BL Direct - All 4 versions
[CITATION] The scaffold protein IB1
JA Haefliger, T Tawadros, L Meylan, SL … - JIP-1 is a critical mediator of cytokine-induced apoptosis …, 2003 Cited by 27 - Related articles
Z Dong, L Zhou, K Del Villar, M Ghanevati, V … - Molecular Brain Research, 2005 - Elsevier We examined if the relative expression of JNK-interacting protein 1 (JIP1) and
phosphorylated c-Jun N-terminal kinase (JNK) regulates cell signaling and
contributes to selective neuronal vulnerability in response to ... Cited by 11 - Related articles - All 3 versions
- ►endojournals.org H Abe, K Murao, H Imachi, WM Cao, X Yu, K … - Endocrinology, 2004 - Endocrine Soc Islet-brain-1 (IB1)/c-Jun N-terminal kinase interacting protein 1 (JIP-1) is a
scaffold protein that is expressed at high levels in neurons and the endocrine
pancreas. IB1/JIP-1 interacts with the c-Jun N-terminal kinase and mediates ... Cited by 5 - Related articles - BL Direct - All 3 versions
- ►cshlp.org NJ Kennedy, G Martin, AG Ehrhardt, J … - Genes & Development, 2007 - genesdev.cshlp.org JIP scaffold proteins are implicated in the regulation of protein kinase signal
transduction pathways. To test the physiological role of these scaffold
proteins, we examined the phenotype of compound mutant mice that lack ... Cited by 7 - Related articles - BL Direct - All 7 versions
- ►nih.gov F Dajas-Bailador, EV Jones, AJ Whitmarsh - Current Biology, 2008 - Elsevier The development of neuronal polarity is essential for the determination of
neuron connectivity and for correct brain function. The c-Jun N-terminal kinase
(JNK)-interacting protein-1 (JIP1) is highly expressed in neurons and has ... Cited by 8 - Related articles - All 8 versions
D Nihalani, HN Wong, LB Holzman - Journal of Biological Chemistry, 2003 - ASBMB JIP1 is a scaffold protein that assembles and facilitates the activation of the
mixed lineage kinase-dependent JNK module. Results of earlier work led us to
propose a model for JIP1-JNK complex regulation that predicts that under ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►jbc.org C Bonny, A Oberson, M Steinmann, DF … - Journal of Biological Chemistry, 2000 - ASBMB IB1/JIP-1 is a scaffold protein that interacts with upstream components of the
c-Jun N-terminal kinase (JNK) signaling pathway. IB1 is expressed at high levels
in pancreatic cells and may therefore exert a tight control on signaling ... Cited by 104 - Related articles - BL Direct - All 5 versions
- ►biologists.org T Tawadros, A Formenton, J Dudler, N … - Journal of cell science, 2002 - jcs.biologists.org The c-Jun N-terminal kinase (JNK) is critical for cell survival,
differentiation, apoptosis and tumorigenesis. This signalling pathway requires
the presence of the scaffold protein Islet-Brain1/c-Jun N-terminal kinase ... Cited by 10 - Related articles - BL Direct - All 4 versions
[CITATION] Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the …