- ►umich.edu [PDF] MK Treutelaar, JM Skidmore, CL Dias-Leme, M Hara, L … - Diabetes, 2003 - Am Diabetes Assoc To clarify the lineage relationship between cells that express the neural stem cell marker nestin
and endocrine cells of the pancreas, we analyzed offspring of a cross between mice carrying
a nestin promoter/enhancer-driven cre-recombinase (Nestin-cre) and C57BL/6J-Gtrosa26 ... Cited by 114 - Related articles - BL Direct - All 5 versions
RK Humphrey, N Bucay, GM Beattie, A Lopez, CA … - Diabetes, 2003 - Am Diabetes Assoc Studies using adult human islets and mouse embryonic stem cells have suggested that the neurepithelial
precursor cell marker nestin also identifies and can be used to purify β-cell precursors. To determine
whether nestin can be used to identify β-cell progenitors in the developing human ... Cited by 68 - Related articles - BL Direct - All 4 versions
A Delacour, V Nepote, A Trumpp, PL Herrera - Mechanisms of development, 2004 - Elsevier Expression of nestin has been suggested to be a characteristic of pancreatic islet stem cells.
To determine whether nestin is indeed expressed in such putative cells during embryonic
development, or in the adult pancreas after injury, we performed a cell lineage analysis ... Cited by 82 - Related articles - All 4 versions
L Selander, H Edlund - Mechanisms of development, 2002 - Elsevier Stem cell research and the prospect of stem cell based therapies depend critically on the identification
of specific markers that can be used for the identification and selection of stem and progenitor
cells. Nestin is expressed in neuronal progenitor cells and has also been suggested to ... Cited by 128 - Related articles - All 5 versions
- ►jhc.org T Klein, Z Ling, H Heimberg, OD Madsen, … - … of Histochemistry and …, 2003 - Histochemical Soc In this study we examined the expression of nestin in islets, the exocrine part, and the big ducts
of the adult human pancreas by immunofluorescent double staining. Two different anti-nestin
antisera in combination with various pancreatic and endothelial markers were employed. ... Cited by 72 - Related articles - BL Direct - All 3 versions
F Esni, DA Stoffers, T Takeuchi, SD Leach - Mechanisms of development, 2004 - Elsevier During pancreatic development, endocrine and exocrine cell types arise from common precursors
in foregut endoderm. However, little information is available regarding regulation of pancreatic
epithelial differentiation in specific precursor populations. We show that undifferentiated ... Cited by 69 - Related articles - All 5 versions
H Huang, X Tang - Laboratory Investigation, 2003 - nature.com Demand for donations to meet the requirements of pancreas or islet transplantation has prompted
the search for alternative sources of -cell replacement therapy. Earlier studies identified
nestin-positive islet-derived progenitor cells (NIPs) residing in human pancreas. In the ... Cited by 57 - Related articles - BL Direct - All 4 versions
J Lardon, I Rooman, L Bouwens - Histochemistry and cell biology, 2002 - Springer Abstract Nestin is an intermediate filament protein expressed by neuroepithelial stem cells and
which has been proposed to represent also a marker for putative islet stem cells. The aim of this
study was to characterize the cell type(s) expressing nestin in the rat pancreas. By ... Cited by 126 - Related articles - BL Direct - All 3 versions
E Hunziker, M Stein - Biochemical and Biophysical Research …, 2000 - Elsevier The pancreatic islets of Langerhans produce several peptide hormones, predominantly the metabolically
active hormones insulin and glucagon, which are critical for maintaining normal fuel
homeostasis. Some evidence exists that pancreatic endocrine cells turn over at a slow ... Cited by 135 - Related articles - BL Direct - All 5 versions
K Piper, S Ball, L Turnpenny, S Brickwood, D Wilson, N … - Diabetologia, 2002 - Springer Human embryonic and foetal pancreas was collected with appropriate ethical approval,
staged, and fixed in 4% parafor- maldehyde [3]. Paraffin-embedded sections, mounted on glass
slides, were dewaxed and subject to immunohistochemistry us- ing the exact protocol and ... Cited by 39 - Related articles - BL Direct - All 4 versions
