- ►diabetesjournals.org M Kitada, D Koya, T Sugimoto, M Isono, S … - Diabetes, 2003 - Am Diabetes Assoc Oxidative stress is implicated to play an important role in the development of
diabetic vascular complications, including diabetic nephropathy. It is unclear
whether oxidative stress is primarily enhanced in the diabetic glomeruli or ... Cited by 121 - Related articles - BL Direct - All 4 versions
T Etoh, T Inoguchi, M Kakimoto, N Sonoda, K … - Diabetologia, 2003 - Springer Aim/hypothesis. An increased production of reactive oxygen species (ROS) could
contribute to the devel- opment of diabetic nephropathy. NAD(P)H oxidase might
be an important source of ROS production in kidney as reported in blood ... Cited by 79 - Related articles - BL Direct - All 3 versions
- ►asnjournals.org JM Li, AM Shah - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol The NADPH oxidase was originally discovered in neutrophils, where it is a potent
source of millimolar quantities of superoxide (O 2 - ) during phagocytosis and
plays a vital role in nonspecific host defense (1). It comprises a membrane- ... Cited by 104 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org [PDF] SA Jones, JT Hancock, OT Jones, A Neubauer … - Journal of the American Society of Nephrology, 1995 - Am Soc Nephrol Page 1. Journal of the American Sociely of Nephrology 1483 The Expression
of NADPH Oxidase Components in Human Glomerular Mesangial ... Cited by 114 - Related articles - BL Direct - All 3 versions
- ►asnjournals.org HB Lee, MR Yu, Y Yang, Z Jiang, H Ha - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Diabetic nephropathy is characterized by excessive deposition of extracellular
matrix (ECM) in the kidney, leading to glomerular mesangial expansion and
tubulointerstitial fibrosis. Clinical studies (1,2) have demonstrated that ... Cited by 174 - Related articles - BL Direct - All 7 versions
K Asaba, A Tojo, ML Onozato, A Goto, MT … - Kidney international, 2005 - nature.com Received 27 July 2004; Revised 7 November 2004; Accepted 19 November 2004. ...
Effects of NADPH oxidase inhibitor in diabetic nephropathy. ... We used
apocynin to test the hypothesis that superoxide anion (O - 2 ) from ... Cited by 80 - Related articles - All 4 versions
- ►asnjournals.org T Inoguchi, T Sonta, H Tsubouchi, T Etoh, M … - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Hyperglycemia seems to be an important causative factor in the development of
micro- and macrovascular complications in patients with diabetes (1,2). Various
pathophysiological and biochemical mechanisms have been proposed to explain ... Cited by 126 - Related articles - BL Direct - All 5 versions
- ►jbc.org H Hua, S Munk, H Goldberg, IG Fantus, CI … - Journal of Biological Chemistry, 2003 - ASBMB High glucose (HG) is the underlying factor contributing to long term
complications of diabetes mellitus. The molecular mechanisms transforming the
glomerular mesangial cell phenotype to cause nephropathy including ... Cited by 45 - Related articles - All 3 versions
ML Onozato, A Tojo, A Goto, T Fujita, CS … - Kidney international, 2002 - nature.com After two weeks of streptozotocin-induced DM, rats received either no treatment,
an angiotensin-converting enzyme inhibitor (ACEI) or an angiotensin receptor
blocker (ARB) for two weeks. At four weeks, renal expression of the p47phox ... Cited by 246 - Related articles - BL Direct - All 6 versions
- ►fasebj.org D KOYA, M HANEDA, H NAKAGAWA, K … - The FASEB Journal, 2000 - FASEB Activation of protein kinase C (PKC) is implicated as an important mechanism by
which diabetes causes vascular complications. We have recently shown that a PKC
ß inhibitor ameliorates not only early diabetes-induced glomerular ... Cited by 276 - Related articles - BL Direct - All 4 versions
