F Castro-Chavez, VK Yechoor, PK Saha, J … - Diabetes, 2003 - Am Diabetes Assoc Obesity is a major risk factor for diabetes and heart disease. We previously
reported that the inactivation of the gene for perilipin (plin), an adipocyte
lipid droplet surface protein, produced lean and obesity-resistant mice. To ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►endojournals.org PA Kern, G Di Gregorio, T Lu, N Rassouli, G … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc The perilipins are highly phosphorylated adipocyte proteins that are localized
at the surface of the lipid droplet. With activation by protein kinase A,
perilipins translocate away from the lipid droplet and allow ... Cited by 38 - Related articles - BL Direct - All 6 versions
PK Saha, H Kojima, J Martinez-Botas, AL … - Journal of Biological Chemistry, 2004 - ASBMB Targeted disruption of the lipid droplet protein, perilipin, in mice leads to
constitutional lipolysis associated with marked reduction in white adipose
tissue as a result of unbridled lipolysis. To investigate the metabolic ... Cited by 27 - Related articles - BL Direct - All 8 versions
Y Wang, S Sullivan, M Trujillo, MJ Lee, SH … - Obesity, 2003 - nature.com Results: Perilipin A (periA) was the major perilipin expressed in adipose
tissues. periA mRNA relative abundance was significantly lower in Sc adipose
tissue from severely obese compared to that from nonobese subjects. Western ... Cited by 48 - Related articles - BL Direct - All 3 versions
- ►endojournals.org S Nagai, C Shimizu, M Umetsu, S Taniguchi, … - Endocrinology, 2004 - Endocrine Soc Perilipin, a family of phosphoproteins located around lipid droplets in
adipocytes, is essential for enlargement of lipid droplets and lipolytic
reaction by hormone-sensitive lipase. Thiazolidinediones, peroxisome ... Cited by 34 - Related articles - BL Direct - All 4 versions
S Mottagui-Tabar, M Ryden, P Löfgren, G … - Diabetologia, 2003 - Springer Aims/hypothesis. We investigated the role of the adi- pocyte-specific protein
perilipin for lipolysis in hu- mans. Methods. Perilipin protein content and
lipolysis rates were measured in human subcutaneous fat cells of non-obese ... Cited by 83 - Related articles - BL Direct - All 3 versions
- ►jbc.org N Arimura, T Horiba, M Imagawa, M Shimizu, … - Journal of Biological Chemistry, 2004 - ASBMB Recent studies have shown that lipid droplets are covered with a proteinaceous
coat, although the functions and identities of the component proteins have not
yet been well elucidated. The first identified lipid droplet-specific ... Cited by 67 - Related articles - BL Direct - All 5 versions
FA Middleton, EJB Ramos, Y Xu, H Diab, X … - Nutrition, 2004 - Elsevier To quantify the relative levels of different messages in different samples, the
RNA is purified from these samples and labeled with a detectable marker. The
labeled samples are then added to a special buffer and placed on the ... Cited by 24 - Related articles - All 6 versions
V Puri, S Konda, S Ranjit, M Aouadi, A … - Journal of Biological Chemistry, 2007 - ASBMB Fat-specific protein (FSP)27/Cidec is most highly expressed in white and brown
adipose tissues and increases in abundance by over 50-fold during adipogenesis.
However, its function in adipocytes has remained elusive since its ... Cited by 34 - Related articles - All 7 versions
