- ►diabetesjournals.org B Zhang, M Hosaka, Y Sawada, S Torii, S Mizutani, M … - Diabetes, 2003 - Am Diabetes Assoc Parathyroid hormone–related protein (PTHrP) increases the content and mRNA level of insulin
in a mouse β-cell line, MIN6, and primary-cultured mouse islets. We examined the mechanism
of PTHrP-induced insulin expression. The PTHrP effect was markedly augmented by ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] D Plows, P Briassouli, C Owen, V … - Biochemical …, 2002 - pubmedcentral.nih.gov The Ras family of GTP-binding proteins are key transducers of extracellular signals, particularly
through the mitogen-activated protein kinase (MAPK) pathway. Constitutively active forms of
Ras are found in a variety of tumours, suggesting an important role for this pathway in ... Cited by 11 - Related articles - BL Direct - All 12 versions
- ►nih.gov [PDF] MR Lornejad-Schäfer, C Schäfer, D Graf, D … - Biochemical …, 2003 - pubmedcentral.nih.gov A contribution of intracellular dehydration to insulin resistance has been established in human
subjects and in different experimental systems. Here the effect of hyperosmolarity (405
mosmol\l) on insulin-induced mitogen-activated protein (MAP) kinase phosphatase ... Cited by 12 - Related articles - BL Direct - All 6 versions
[CITATION] Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by …
- ►jbc.org T Kayo, Y Sawada, Y Suzuki, M Suda, S Tanaka, Y … - Journal of Biological …, 1996 - ASBMB Prohormone convertases PC2 and PC3, yeast Kex2-family endoproteases specific to the regulated
secretory pathway, cleave proinsulin to insulin in the secretory granules of pancreatic cells. The
well-differentiated cell line MIN6 expresses PC2 and PC3 and another regulated ... Cited by 25 - Related articles - BL Direct - All 4 versions
P Stawowy, S Goetze, C Margeta, E Fleck, K Graf - Biochemical and Biophysical …, 2003 - Elsevier Activation of MAPK pathways by angiotensin II (Ang II) is important for cardiac fibroblast
(CFB) proliferation and migration. Activity of MAP-kinases is closely controlled by a group of
dual-specific MAP kinase phosphatases (MKPs). Lipopolysaccharides (LPS) and ... Cited by 14 - Related articles - All 3 versions
[CITATION] Osteopontin mediates hypoxia-induced proliferation of cultured mesangial cells: …
- ►endocrinology-journals.org [PDF] ML Villanueva-Penacarrillo, J Cancelas, F de … - Journal of …, 1999 - Soc Endocrinology Parathyroid hormone (PTH)-related protein (PTHrP) is present in the pancreatic islet. Recent
data in transgenic mice suggest that PTHrP might modulate islet mass and insulin secretion.
In the present study, we assessed the effect of the N-terminal PTH-like region of PTHrP on ... Cited by 16 - Related articles - All 6 versions
V Vongthavaravat, S Mesiya, L Saymeh, Y Xia, RF … - Digestive diseases and …, 2003 - Springer The mechanisms by which transforming growth factor-α (TGF-α) protects the stomach against
mu- cosal injury are incompletely understood. The aim of this study was to examine the roles
of sensory neurons, sensory neuropeptides and prostaglandins in TGFα gastroprotection ... Cited by 7 - Related articles - All 4 versions
H Takagi, T Fukusato, U Kawaharada, SI … - Digestive diseases and …, 1997 - Springer Hypertrophic gastric mucosa in transgenic mice overexpressing transforming growth factor
(TGF)-a showed mucosal cellular hyperplasia with dysplasia, suppression of gastric acid
secretion, and chief and parietal cell depletion. In order to clarify the effects of TGF-a on ... Cited by 7 - Related articles - BL Direct - All 4 versions
