E Bell, X Cao, JA Moibi, SR Greene, R Young, … - Diabetes, 2003 - Am Diabetes Assoc Rapamycin (sirolimus) is a macrolide fungicide with immunosuppressant properties
that is used in human islet transplantation. Little is known about the effects
of rapamycin on MIN-6 cells and islets. Rapamycin had a dose-dependent, ... Cited by 73 - Related articles - BL Direct - All 4 versions
NM Desai, JA Goss, S Deng, BA Wolf, E … - Transplantation, 2003 - journals.lww.com Desai, Niraj M.; Goss, John A.; Deng, Shaoping; Wolf, Bryan A.; Markmann,
Eileen; Palanjian, Maral; Shock, Angela P.; Feliciano, Sue; Brunicardi, F.
Charles; Barker, Clyde F.; Naji, Ali; Markmann, James F. Cited by 48 - Related articles - BL Direct - All 3 versions
AM Shapiro, HL Gallant, EG Hao, JRT Lakey, … - Therapeutic drug monitoring, 2005 - journals.lww.com Abstract: Outcomes in clinical islet transplantation improved substantially with
the introduction of combined sirolimus and tacrolimus immunosuppression.
However, multiple islet preparations are often required to achieve insulin ... Cited by 41 - Related articles - All 4 versions
- ►diabetesjournals.org N Zhang, D Su, S Qu, T Tse, R Bottino, AN … - Diabetes, 2006 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large
quantities of islets, but only a fraction of transplanted islets can survive and
become engrafted, and yet the underlying mechanism remains unclear. In this ... Cited by 41 - Related articles - BL Direct - All 7 versions
NM Kneteman, JRT Lakey, T Wagner, D … - Transplantation, 1996 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 35 - Related articles - BL Direct - All 3 versions
- ►endojournals.org JC Lopez-Talavera, A Garcia-Ocana, I Sipula, … - Endocrinology, 2004 - Endocrine Soc Islet transplantation for diabetes is limited by the availability of human islet
donors. Hepatocyte growth factor (HGF) is a potent ß-cell mitogen and survival
factor and improves islet transplant outcomes in a murine model. However, ... Cited by 62 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org H Hui, N Khoury, X Zhao, L Balkir, ED'Amico, A … - Diabetes, 2005 - Am Diabetes Assoc Immunosuppressive drugs are routinely used to provide tolerance after whole
pancreas and islet cell transplantations. While they are essential in inhibiting
graft rejection, little is known about their effect on islet function and ... Cited by 32 - Related articles - All 5 versions
C RICORDI, Y ZENG, R ALEJANDRO, A … - Transplantation, 1991 - journals.lww.com September 1991 RICORDI ET AL. 519 pathogenic and sympathizing eyes. Arch
Ophthalmol 1964; 72: 9. 12. Niederkorn JY, Shadduck JA, Streilein JW.
Immunogenetic basis for immunologic privilege in the anterior chamber of ... Cited by 70 - Related articles - All 3 versions
CT Bussiere, JRT Lakey, AMJ Shapiro, GS … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis The Edmonton Protocol for islet trans- plantation has
provided hope for type 1 diabetic patients. However, this protocol requires
lifelong immunosuppres- sion, specifically sirolimus, a cellular ... Cited by 28 - Related articles - BL Direct - All 4 versions