- ►diabetesjournals.org M Hawkins, J Tonelli, P Kishore, D Stein, E Ragucci, A … - Diabetes, 2003 - Am Diabetes Assoc Increased circulating free fatty acids (FFAs) inhibit both hepatic and peripheral insulin action.
Because the loss of effectiveness of glucose to suppress endogenous glucose production and
stimulate glucose uptake contributes importantly to fasting hyperglycemia in type 2 ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org M Hawkins, I Gabriely, R Wozniak, K Reddy, L Rossetti, … - Diabetes, 2002 - Am Diabetes Assoc Glucose effectiveness is impaired in type 2 diabetes. We hypothesize that chronic hyperglycemia
and hyperlipidemia contribute importantly to this defect. To test this hypothesis, we compared
the effect of acute hyperglycemia on glucose turnover in type 2 diabetic subjects in good ... Cited by 29 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] M Mevorach, A Giacca, Y Aharon, M … - Journal of Clinical …, 1998 - pubmedcentral.nih.gov We examined the ability of an equivalent increase in circu- lating glucose concentrations to inhibit
endogenous glucose production (EGP) and to stimulate glucose metabolism in patients with
Type 2 diabetes mellitus (DM2). Somatostatin was infused in the presence of basal ... Cited by 74 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org P Kishore, J Tonelli, S Koppaka, C Fratila, A Bose, DE … - Diabetes, 2006 - Am Diabetes Assoc Impaired effectiveness of glucose to suppress endogenous glucose production (EGP) is an important
cause of worsening hyperglycemia in type 2 diabetes. Elevated free fatty acids (FFAs) may impair
glucose effectiveness via several mechanisms, including rapid changes in metabolic ... Cited by 5 - Related articles - BL Direct - All 5 versions
S Nagasaka, K Tokuyama, I Kusaka, H … - DIABETES-NEW …, 1999 - Am Diabetes Assoc Insulin sensitivity, glucose effectiveness, and endoge- nous glucose production (EGP) during
stable-labeled, frequently sampled insulin-modified intravenous glu- cose tolerance test
(FSIGT) were evaluated by a single- and two-compartment minimal model combined with ... Cited by 37 - Related articles - BL Direct - All 6 versions
[CITATION] Effect of hyperglycemia on glucose production and utilization in humans
S Kehlenbrink, J Tonelli, S Koppaka, V … - American Journal of …, 2009 - Am Physiological Soc Glucose effectiveness, the ability of glucose per se to suppress endogenous glucose production
(EGP), is lost in type 2 diabetes mellitus (T2DM). Free fatty acids (FFA) may contribute to this
loss of glucose effectiveness in T2DM by increasing gluconeogenesis (GNG) and ... Related articles - All 3 versions
[CITATION] The effect of glycemic control on hepatic and peripheral glucose effectiveness in …
