- ►diabetesjournals.org MG de Vries, LM Arseneau, ME Lawson, JL Beverly - Diabetes, 2003 - Am Diabetes Assoc The activity of neurons in the ventromedial hypothalamus (VMH) important for initiating compensatory
responses to hypoglycemia is influenced by ambient glucose concentration. In the present
study, we used in vivo microdialysis to evaluate interstitial glucose concentrations in rat ... Cited by 65 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Z Song, BE Levin, JJ McArdle, N Bakhos, VH Routh - Diabetes, 2001 - Am Diabetes Assoc Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) were studied using
visually guided slice-patch recording techniques in brain slices from 14- to 21-day-old male
Sprague-Dawley rats. Whole-cell current-clamp recordings were made as extracellular ... Cited by 119 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org R Wang, X Liu, ST Hentges, AA Dunn-Meynell, BE … - Diabetes, 2004 - Am Diabetes Assoc Glucosensing neurons in the hypothalamic arcuate nucleus (ARC) were studied using electrophysiological
and immunocytochemical techniques in neonatal male Sprague-Dawley rats. We identified
glucose-excited and -inhibited neurons, which increase and decrease, respectively, their ... Cited by 106 - Related articles - BL Direct - All 5 versions
L Kang, VH Routh, EV Kuzhikandathil, LD Gaspers, BE … - Diabetes, 2004 - Am Diabetes Assoc To evaluate potential mechanisms for neuronal glucosensing, fura-2 Ca 2+ imaging and
single-cell RT-PCR were carried out in dissociated ventromedial hypothalamic nucleus
(VMN) neurons. Glucose-excited (GE) neurons increased and glucose-inhibited (GI) ... Cited by 94 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org Z Song, VH Routh - Diabetes, 2005 - Am Diabetes Assoc Glucose directly alters the action potential frequency of glucosensing neurons in the ventromedial
hypothalamic nucleus (VMN). Glucose-excited neurons increase, and glucose-inhibited neurons
decrease, their action potential frequency as glucose increases from 0.1 to 2.5 mmol/l. ... Cited by 61 - Related articles - All 7 versions
- ►jneurosci.org [PDF] IA Silver, M Erecinska - Journal of Neuroscience, 1994 - Soc Neuroscience The mammalian CNS relies on a constant supply of external glucose for its undisturbed
operation. Under normal circum- stances other fuels, such as fatty acids or ketone bodies, play
only a very minor role (Siesjo, 1978) while endogenous stores ofglycogen are relatively ... Cited by 173 - Related articles - BL Direct - All 5 versions
EC McNay, PE Gold - Journal of neurochemistry, 1999 - interscience.wiley.com Abstract : The concentration of glucose in the brain's extracellular fluid remains
controversial, with recent estimates and measurements ranging from 0.35 to 3.3 mM. In the present
experiments, we used the method of zero-net-flux microdialysis to determine glucose ... Cited by 70 - Related articles - BL Direct - All 4 versions
AA Dunn-Meynell, VH Routh, L Kang, L Gaspers, BE … - Diabetes, 2002 - Am Diabetes Assoc Specialized neurons utilize glucose as a signaling molecule to alter their firing rate.
Glucose-excited (GE) neurons increase and glucose-inhibited (GI) neurons reduce activity as
ambient glucose levels rise. Glucose-induced changes in the ATP-to-ADP ratio in GE ... Cited by 116 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org L Kang, AA Dunn-Meynell, VH Routh, LD Gaspers, Y … - Diabetes, 2006 - Am Diabetes Assoc To test the hypothesis that glucokinase is a critical regulator of neuronal glucosensing, glucokinase
activity was increased, using a glucokinase activator drug, or decreased, using RNA interference
combined with calcium imaging in freshly dissociated ventromedial hypothalamic nucleus ... Cited by 49 - Related articles - BL Direct - All 7 versions
- ►physiology.org R Wang, C Cruciani-Guglielmacci, S … - Journal of …, 2006 - Am Physiological Soc Pharmacological manipulation of fatty acid metabolism in the hypothalamic arcuate nucleus
(ARC) alters energy balance and glucose homeostasis. Thus, we tested the hypotheses that
distinctive populations of ARC neurons are oleic acid (OA) sensors that exhibit a glucose ... Cited by 35 - Related articles - BL Direct - All 4 versions
