AP Russell, J Feilchenfeldt, S Schreiber, M Praz, A … - Diabetes, 2003 - Am Diabetes Assoc The peroxisome proliferator-activated receptor (PPAR)-γ coactivator-1 (PGC-1) can induce mitochondria
biogenesis and has been implicated in the development of oxidative type I muscle fibers. The
PPAR isoforms α, β/δ, and γ control the transcription of genes involved in fatty acid and ... Cited by 137 - Related articles - BL Direct - All 6 versions
- ►physiology.org J Norrbom, CJ Sundberg, H Ameln, WE … - Journal of Applied …, 2004 - Am Physiological Soc Endurance training leads to many adaptational changes in several tissues. In skeletal
muscle, fatty acid usage is enhanced and mitochondrial content is increased. The exact molecular
mechanisms regulating these functional and structural changes remain to be elucidated. ... Cited by 98 - Related articles - BL Direct - All 6 versions
- ►fasebj.org K Baar, AR Wende, TE Jones, M Marison, LA Nolte, … - The FASEB Journal, 2002 - FASEB Endurance exercise induces increases in mitochondria and the GLUT4 isoform of the glucose
transporter in muscle. Although little is known about the mechanisms underlying these
adaptations, new information has accumulated regarding how mitochondrial biogenesis ... Cited by 293 - Related articles - BL Direct - All 5 versions
H Pilegaard, B Saltin, PD Neufer - The Journal of Physiology, 2003 - Physiological Soc Endurance exercise training induces mitochondrial biogenesis in skeletal muscle. The peroxisome
proliferator activated receptor co-activator 1α (PGC-1α) has recently been identified as a nuclear
factor critical for coordinating the activation of genes required for mitochondrial ... Cited by 240 - Related articles - BL Direct - All 6 versions
S Terada, M Goto, M Kato, K Kawanaka, T … - … and biophysical research …, 2002 - Elsevier We previously reported that the peroxisome proliferator-activated receptor γ coactivator-1
(PGC-1) mRNA in rat epitrochlearis muscle was increased after swimming exercise training.
In the present study, we demonstrated further that PGC-1 mRNA expression in the ... Cited by 148 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] AP Russell, MKC Hesselink, SK Lo, P Schrauwen - The FASEB Journal, 2005 - FASEB The FASEB Journal express article 10.1096/fj.04-3168fje. Published online April 6, 2005. ...
Regulation of metabolic transcriptional co-activators and ... *Clinique Romande de Réadaptation
SUVA Care, Sion, Switzerland; ... Corresponding author: Aaron P. Russell, Clinique ... Cited by 60 - Related articles - All 5 versions
- ►pnas.org C Handschin, J Rhee, J Lin, PT Tarr, BM … - Proceedings of the …, 2003 - National Acad Sciences Skeletal muscle adapts to chronic physical activity by inducing mitochondrial biogenesis and
switching proportions of muscle fibers from type II to type I. Several major factors involved in this
process have been identified, such as the calcium/calmodulin-dependent protein kinase ... Cited by 217 - Related articles - BL Direct - All 10 versions
M Goto, S Terada, M Kato, M Katoh, T Yokozeki, I … - … and Biophysical Research …, 2000 - Elsevier Peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1), a cold-inducible coactivator
of nuclear receptors, stimulates mitochondrial biogenesis and respiration in muscle cells. In the
present study, we first cloned a rat PGC-1 gene from a brown adipose tissue cDNA library ... Cited by 140 - Related articles - BL Direct - All 6 versions
J Lin, H Wu, PT Tarr, CY Zhang, Z Wu, O Boss, LF … - Nature, 2002 - nature.com The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not well
understood. In addition to the expression of particular myofibrillar proteins, type I
(slow-twitch) fibres are much higher in mitochondrial content and are more dependent on ... Cited by 720 - Related articles - BL Direct - All 8 versions
- ►physiology.org RJ Tunstall, KA Mehan, GD Wadley, GR … - American Journal of …, 2002 - Am Physiological Soc The effects of a single bout of exercise and exercise training on the expression of genes necessary
for the transport and -oxidation of fatty acids (FA), together with the gene expression of transcription
factors implicated in the regulation of FA homeostasis were investigated. Seven human ... Cited by 139 - Related articles - BL Direct - All 4 versions
