- ►diabetesjournals.org G Murdolo, P Lucidi, C Di Loreto, N Parlanti, A De … - Diabetes, 2003 - Am Diabetes Assoc Accumulating evidence indicates that ghrelin plays a role in regulating food intake and energy
homeostasis. In normal subjects, circulating ghrelin concentrations decrease after meal ingestion
and increase progressively before meals. At present, it is not clear whether nutrients ... Cited by 114 - Related articles - BL Direct - All 9 versions
- ►physiology.org DE Flanagan, ML Evans, TP Monsod, F … - American Journal of …, 2003 - Am Physiological Soc Ghrelin is a novel peptide that acts on the growth hormone (GH) secretagogue receptor in the
pituitary and hypothalamus. It may function as a third physiological regulator of GH
secretion, along with GH-releasing hormone and somatostatin. In addition to the action of ... Cited by 180 - Related articles - BL Direct - All 3 versions
M Möhlig, J Spranger, B Otto, M Ristow, M … - Journal of …, 2002 - ncbi.nlm.nih.gov The orexigenic and anabolic gastric hormone ghrelin is secreted in response to acute and chronic
energy requirements. While pre-prandial increases and post-prandial decreases of plasma ghrelin
levels in rodents and humans seem to indicate a role for the novel peptide hormone as an ... Cited by 136 - Related articles - BL Direct - All 6 versions
J Spranger, M Ristow, B Otto, W Heldwein, M … - Journal of …, 2003 - ncbi.nlm.nih.gov Ghrelin is the most powerful orexigenic hormone in mammalian physiology. Ghrelin plasma concentrations
increase prior to meal onset, but decrease post-prandially. We and others reported previously
that insulin reduces circulating ghrelin levels and might therefore be a driving force for ... Cited by 20 - Related articles - BL Direct - All 3 versions
MF Saad, B Bernaba, CM Hwu, S Jinagouda, S … - Journal of Clinical …, 2002 - Endocrine Soc Ghrelin is a novel gastric peptide which stimulates growth hormone and has orexigenic and adipogenic
properties. Plasma ghrelin is influenced by nutritional status and is thought to play a role in regulating
food intake and body weight. We examined the effect of infusing insulin (40 mU/m 2 /min) ... Cited by 280 - Related articles - BL Direct - All 6 versions
G Schaller, A Schmidt, J Pleiner, W Woloszczuk, M … - Diabetes, 2003 - Am Diabetes Assoc Ghrelin plasma concentrations increase during fasting and fall rapidly after nutrient
ingestion. We hypothesized that insulin or glucose could regulate ghrelin secretion by a feedback
mechanism. In this randomized, double-blind, placebo-controlled crossover study, three ... Cited by 145 - Related articles - BL Direct - All 4 versions
- ►endojournals.org HS Callahan, DE Cummings, MS Pepe, PA … - Journal of Clinical …, 2004 - Endocrine Soc Plasma ghrelin levels rise before meals and fall rapidly afterward. If ghrelin is a physiological
meal-initiation signal, then a large oral caloric load should suppress ghrelin levels more than
a small caloric load, and the request for a subsequent meal should be predicted by ... Cited by 102 - Related articles - BL Direct - All 5 versions
- ►endojournals.org DL Williams, DE Cummings, HJ Grill, JM Kaplan - Endocrinology, 2003 - Endocrine Soc Plasma ghrelin levels are rapidly suppressed by ingestion or gastric delivery of nutrients. Given
that the majority of circulating ghrelin appears to be of gastric origin, we addressed the contribution
of gastric distention or nutrient sensitivity to this response. Awake, unrestrained rats ... Cited by 97 - Related articles - BL Direct - All 4 versions
A Caixas, C Bashore, W Nash, F Pi-Sunyer, B … - Journal of Clinical …, 2002 - Endocrine Soc Food intake suppresses plasma levels of the gastric peptide ghrelin in humans. We hypothesize
that the food intake- suppression of ghrelin could be secondary to the plasma glucose and insulin
changes after a meal. The aim of this study was to compare the effect of the administration ... Cited by 163 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org C Anderwald, G Brabant, E Bernroider, R Horn, A … - Diabetes, 2003 - Am Diabetes Assoc The gastric peptide ghrelin augments and the adipocyte-derived hormone leptin reduces appetite
and food intake. In the central nervous system, insulin directly decreases hunger sensation but
could also act indirectly by modulating ghrelin and leptin secretion. This study examines ... Cited by 62 - Related articles - BL Direct - All 4 versions
