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Scholar Results 1 - 10 of about 101 related to Drazen: Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. (0.13 sec) 

Adrenalectomy alters the sensitivity of the central nervous system melanocortin system


DL Drazen, MD Wortman, MW Schwartz, DJ … - Diabetes, 2003 - Am Diabetes Assoc
Removal of adrenal steroids by adrenalectomy (ADX) reduces food intake and body
weight in rodents and prevents excessive weight gain in many genetic and dietary
models of obesity. Thus, glucocorticoids appear to play a key role to ...
Cited by 28 - Related articles - BL Direct - All 4 versions

CNS-periphery relationships and body weight homeostasis: influence of the glucocorticoid …


B Jeanrenaud, F Rohner-Jeanrenaud - International journal of obesity and related metabolic …, 2000 - ncbi.nlm.nih.gov
The obesity-like effects produced by the chronic intracerebroventricular (icv)
neuropeptide Y (NPY) infusion in normal rats require the presence of
glucocorticoids, as none of them occurs when NPY is similarly infused in ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in …

- diabetesjournals.org [PDF] 
H Makimura, TM Mizuno, J Roberts, J … - Diabetes, 2000 - Am Diabetes Assoc
In genetically obese leptin-deficient ob/ob mice, adrena- lectomy reverses or
attenuates the obese phenotype. Relative to lean controls, ob/ob mice also
exhibit decreased hypothalamic proopiomelanocortin (POMC) mRNA and ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Intraventricular corticosterone increases the rate of body weight gain in underweight …


PK Green, CW Wilkinson, SC Woods - Endocrinology, 1992 - Endocrine Soc
Page 1. 0013-7227/92/1301-0269$03.00/O Endocrinology Copyright 0 1992 by The
Endocrine Society Vol. 130, No. 1 Printed in USA Intraventricular ...
Cited by 55 - Related articles - All 3 versions

Constitutive activation of STAT-3 and downregulation of SOCS-3 expression induced by …

- physiology.org
AM Madiehe, L Lin, C White, HD Braymer, GA … - … Journal of Physiology- Regulatory, Integrative and …, 2001 - Am Physiological Soc
Removal of adrenal steroids by adrenalectomy (ADX) slows or reverses the
development of many forms of obesity in rodents, including those that are leptin
or leptin receptor deficient. Obesity is associated with hyperleptinemia ...
Cited by 27 - Related articles - BL Direct - All 3 versions

Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A

- endojournals.org
DL Drazen, LM Coolen, AD Strader, MD … - Endocrinology, 2004 - Endocrine Soc
Removal of glucocorticoids by adrenalectomy (ADX) reduces food intake and body
weight in rodents and prevents excessive weight gain in many genetic and dietary
models of obesity. Glucocorticoids play a key role to promote positive ...
Cited by 17 - Related articles - BL Direct - All 5 versions

The effects of glucocorticoids on feeding behavior in rats


SE la Fleur - Physiology & behavior, 2006 - Elsevier
Glucocorticoids have major effects on food intake, however, the underlying
mechanisms are poorly understood. This article highlights data on the changes
that occur when glucocorticoids are removed by adrenalectomy, and the ...
Cited by 12 - Related articles - All 4 versions

Selective dependence of intracerebroventricular neuropeptide Y-elicited effects on central …

- endojournals.org
KE Zakrzewska, A Sainsbury, I Cusin, J … - Endocrinology, 1999 - Endocrine Soc
It has been reported that hyperphagia and excessive body weight gain of
genetically obese rodents were abolished by adrenalectomy. High hypothalamic
levels of neuropeptide Y (NPY) were found in obese rodents. A chronic ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Effects of adrenalectomy on AGRP, POMC, NPY and CART gene expression in the basal …


E Savontaus, IM Conwell, SL Wardlaw - Brain research, 2002 - Elsevier
Glucocorticoids regulate body energy balance through both peripheral and central
mechanisms. In order to understand the central mechanisms that mediate these
effects of glucocorticoids we studied the effects of adrenalectomy (ADX) ...
Cited by 57 - Related articles - All 5 versions

Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of …


AP Coll, BG Challis, M López, S Piper, GSH Yeo … - Diabetes, 2005 - Am Diabetes Assoc
Congenital lack of proopiomelanocortin (POMC) causes obesity and glucocorticoid
deficiency. The responses of Pomc −/− and wild-type mice to the
administration of corticosterone were compared. In study 1, mice were given ...
Cited by 29 - Related articles - BL Direct - All 5 versions


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