- ►diabetesjournals.org S Lam, RN van der Geest, NAM Verhagen, FA … - Diabetes, 2003 - Am Diabetes Assoc Tubulointerstitial fibrosis is an important component in the development of
diabetic nephropathy. Various renal cell types, including fibroblasts,
contribute to the excessive matrix deposition in the kidney. Although ... Cited by 75 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org P Roestenberg, FA van Nieuwenhoven, L … - Diabetes Care, 2004 - Am Diabetes Assoc OBJECTIVE—Connective tissue growth factor (CTGF) is strongly upregulated in
fibrotic disorders and has been hypothesized to play a role in the development
and progression of diabetes complications. The aim of the present study was ... Cited by 65 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org RE Gilbert, A Akdeniz, S Weitz, WR Usinger … - Diabetes Care, 2003 - Am Diabetes Assoc OBJECTIVE—Excretion of growth factors in the urine has been implicated in the
pathogenesis of tubulointerstitial disease that characterizes proteinuric renal
disease. In this cross-sectional study, we sought to examine the urinary ... Cited by 61 - Related articles - BL Direct - All 5 versions
BL Riser, P Cortes, M Denichilo, PV … - Kidney international, 2003 - nature.com It is currently impossible to reliably predict which diabetic patients will
develop nephropathy and progress to kidney failure. Microalbuminuria, often
regarded as a predictor of overt diabetic renal disease is, in fact, an ... Cited by 59 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] P Roestenberg, FA van Nieuwenhoven, JA … - American Journal of Physiology- Renal Physiology, 2006 - Am Physiological Soc 59 articles, 37 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/290/6/F1344#BIBL ... 6 other
HighWire hosted articles, the first 5 are: This article has been cited by Cited by 38 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] NA Wahab, N Yevdokimova, BS Weston, T … - Biochemical Journal, 2001 - pubmedcentral.nih.gov We characterized a rabbit polyclonal antibody raised against human recombinant
connective tissue growth factor (CTGF). The antibody recognised a higher
molecular mass form (approx. 56kDa) of CTGF in mesangial cell lysates as ... Cited by 152 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org H Yokoi, M Mukoyama, T Nagae, K Mori, T … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol ABSTRACT. Connective tissue growth factor (CTGF/CCN2) is one of the candidate
factors mediating fibrogenic activity of TGF- . It was shown previously that the
blockade of CTGF by antisense oligonucleotide (ODN) inhibits TGF- ... Cited by 122 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org NA Wahab, BS Weston, RM Mason - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Connective tissue growth factor (CTGF) is implicated as a factor promoting
tissue fibrosis in several disorders, including diabetic nephropathy. However,
the molecular mechanism(s) by which it functions is not known. CTGF rapidly ... Cited by 43 - Related articles - All 6 versions
- ►endojournals.org SV McLennan, XY Wang, V Moreno, DK Yue, … - Endocrinology, 2004 - Endocrine Soc High glucose concentration inhibits matrix degradation and affects the
activities of the enzymes responsible, the matrix metalloproteinases (MMPs) and
their tissue inhibitors (TIMPs). Connective tissue growth factor (CTGF) ... Cited by 74 - Related articles - BL Direct - All 6 versions
- ►jbc.org R Gao, DR Brigstock - Journal of Biological Chemistry, 2004 - ASBMB Connective tissue growth factor (CCN2, also known as CTGF) is a matricellular
protein that appears to play an important role in hepatic stellate cell
(HSC)-mediated fibrogenesis. After signal peptide cleavage, the full-length ... Cited by 103 - Related articles - BL Direct - All 5 versions
