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Scholar Results 1 - 10 of about 101 related to Combs: Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-spe.... (0.15 sec) 

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific …


TP Combs, AH Berg, MW Rajala, S Klebanov, P … - Diabetes, 2003 - Am Diabetes Assoc
Adiponectin or adipocyte complement-related protein of 30 kDa (Acrp30) is a
circulating protein produced exclusively in adipocytes. Circulating Acrp30
levels have been associated with insulin sensitivity in adult mice and ...
Cited by 223 - Related articles - BL Direct - All 5 versions

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein


H Nishizawa, I Shimomura, K Kishida, N … - Diabetes, 2002 - Am Diabetes Assoc
Adiponectin, an adipose-specific secretory protein, exhibits antidiabetic and
antiatherogenic properties. In the present study, we examined the effects of sex
hormones on the regulation of adiponectin production. Plasma adiponectin ...
Cited by 372 - Related articles - BL Direct - All 5 versions

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin


UB Pajvani, X Du, TP Combs, AH Berg, MW … - Journal of Biological Chemistry, 2003 - ASBMB
Acrp30/adiponectin is an adipocyte-specific secretory protein that has recently
been implicated as a mediator of systemic insulin sensitivity with liver and
muscle as target organs. Acrp30 is found as two forms in serum, as a lower ...
Cited by 505 - Related articles - BL Direct - All 4 versions

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays …

- endojournals.org
TP Combs, UB Pajvani, AH Berg, Y Lin, LA … - Endocrinology, 2004 - Endocrine Soc
Adiponectin is a plasma protein expressed exclusively in adipose tissue.
Adiponectin levels are linked to insulin sensitivity, but a direct effect of
chronically elevated adiponectin on improved insulin sensitivity has not ...
Cited by 206 - Related articles - BL Direct - All 5 versions

Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting …

- jbc.org
A Xu, KW Chan, RLC Hoo, Y Wang, KCB Tan, … - Journal of Biological Chemistry, 2005 - ASBMB
The antidiabetic hormone adiponectin circulates in blood as several oligomeric
complexes, and the ratios between them are critical in determining insulin
sensitivity. In this study we investigated the role of testosterone in ...
Cited by 180 - Related articles - All 5 versions

Prolactin and growth hormone regulate adiponectin secretion and receptor expression in …


L Nilsson, N Binart, M Bohlooly-Y, M Bramnert … - Biochemical and biophysical research communications, 2005 - Elsevier
Adiponectin is a hormone secreted from adipose tissue, and serum levels are
decreased with obesity and insulin resistance. Because prolactin (PRL) and
growth hormone (GH) can affect insulin sensitivity, we investigated the ...
Cited by 55 - Related articles - All 6 versions

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

- nih.gov
TP Combs, AH Berg, S Obici, PE Scherer, L … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig
Intraperitoneal injection of purified recombinant Acrp30 lowers glucose levels
in mice. To gain insight into the mechanism(s) of this hypoglycemic effect,
purified recombinant Acrp30 was infused in conscious mice during a ...
Cited by 599 - Related articles - BL Direct - All 8 versions

Serum adiponectin levels are inversely associated with overall and central fat distribution but …

- endojournals.org
A Gavrila, JL Chan, N Yiannakouris, M … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Adiponectin is an adipocyte-secreted protein that circulates in high
concentrations in the serum and acts to increase insulin sensitivity. Previous
studies have shown that serum adiponectin is inversely associated with fat ...
Cited by 172 - Related articles - BL Direct - All 5 versions

Impaired multimerization of human adiponectin mutants associated with diabetes


H Waki, T Yamauchi, J Kamon, Y Ito, S Uchida … - Journal of Biological Chemistry, 2003 - ASBMB
Adiponectin is an adipocyte-derived hormone, which has been shown to play
important roles in the regulation of glucose and lipid metabolism. Eight
mutations in human adiponectin have been reported, some of which were ...
Cited by 423 - Related articles - BL Direct - All 4 versions

Role of disulfide bonds in Acrp30/Adiponectin structure and signaling specificity


TS Tsao, E Tomas, HE Murrey, C Hug, DH … - Journal of Biological Chemistry, 2003 - ASBMB
Acrp30/adiponectin is an adipocyte-derived serum protein with important roles in
regulation of lipid and glucose metabolism, but which of its isoforms are
biologically active remains controversial. We addressed this issue by first ...
Cited by 231 - Related articles - BL Direct - All 5 versions


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