- ►diabetesjournals.org K Maeda, KT Uysal, L Makowski, CZ Görgün, G … - Diabetes, 2003 - Am Diabetes Assoc The metabolic syndrome is a cluster of metabolic and inflammatory abnormalities
including obesity, insulin resistance, type 2 diabetes, hypertension,
dyslipidemia, and atherosclerosis. The fatty acid binding proteins aP2 ... Cited by 67 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org JB Boord, K Maeda, L Makowski, VR Babaev, S … - Arteriosclerosis, thrombosis, and vascular biology, 2002 - Am Heart Assoc Methods and Results— Mice deficient in aP2 and apolipoprotein E (aP2 -/- apoE
-/- mice) and apolipoprotein E–deficient control mice (apoE -/- mice) were fed
a Western diet for 14 weeks. No significant differences in fasting serum ... Cited by 69 - Related articles - BL Direct - All 8 versions
- ►nutrition.org L Makowski, GS Hotamisligil - Journal of Nutrition, 2004 - Am Soc Nutrition Insulin resistance, cardiovascular disease, hypertension, and dyslipidemia are
all closely linked with obesity in the cluster of pathologies known as the
Metabolic Syndrome (1). Obesity can be considered a chronic inflammatory ... Cited by 67 - Related articles - All 3 versions
- ►diabetesjournals.org [PDF] L Scheja, L Makowski, KT Uysal, SM … - Diabetes, 1999 - Am Diabetes Assoc Recent studies have shown that genetic deficiency of the adipocyte fatty
acid–binding protein (aP2) results in minor alterations of plasma lipids and
adipocyte devel- opment but provides significant protection from dietary ... Cited by 89 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org JB Boord, K Maeda, L Makowski, VR Babaev, S … - Circulation, 2004 - Am Heart Assoc From the Research Department and Geriatric Research, Education, and Clinical
Center, VA Tennessee Valley Healthcare System, Nashville (JBB); Department of
Genetics and Complex Diseases, Harvard School of Public Health, Boston, ... Cited by 55 - Related articles - BL Direct - All 6 versions
- ►cell.com K Maeda, H Cao, K Kono, CZ Gorgun, M … - Cell Metabolism, 2005 - Elsevier Fatty acid binding proteins (FABPs) are cytosolic fatty acid chaperones whose
biological role and mechanisms of action are not well understood. Here, we
developed mice with targeted mutations in two related adipocyte FABPs, aP2 ... Cited by 107 - Related articles - All 13 versions
KT Uysal, L Scheja, SM Wiesbrock, S Bonner- … - Endocrinology, 2000 - Endocrine Soc Adipocyte fatty acid-binding protein, aP2, is a member of the intracellular
fatty acid binding protein family. Previously, studies have shown increased
insulin sensitivity in aP2-deficient mice with dietary obesity. Here, we ... Cited by 95 - Related articles - BL Direct - All 4 versions
- ►jlr.org D Zimmer, S Jennifer, DF Dyckes, DA … - The Journal of Lipid Research, 2004 - ASBMB Leukotriene A 4 (LTA 4 ) is a chemically reactive conjugated triene epoxide
product derived from 5-lipoxygenase oxygenation of arachidonic acid. At
physiological pH, this reactive compound has a half-life of less than 3 s ... Cited by 18 - Related articles - BL Direct - All 4 versions
L Makowski, JB Boord, K Maeda, VR Babaev, KT … - Nature Medicine, 2001 - nature.com The adipocyte fatty-acid−binding protein, aP2, has an important role in
regulating systemic insulin resistance and lipid metabolism. Here we demonstrate
that aP2 is also expressed in macrophages, has a significant role in their ... Cited by 174 - Related articles - BL Direct - All 4 versions
L Makowski, KC Brittingham, JM Reynolds, J … - Journal of Biological Chemistry, 2005 - ASBMB Fatty acid-binding proteins are cytosolic fatty acid chaperones, and the
adipocyte isoform, aP2, plays an important role in obesity and glucose
metabolism. Recently, this protein has been detected in macrophages where ... Cited by 72 - Related articles - All 5 versions
