- ►diabetesjournals.org K Nonogaki, L Abdallah, EH Goulding, SJ Bonasera, … - Diabetes, 2003 - Am Diabetes Assoc We have observed late-onset obesity in mutant mice lacking the serotonin 5-HT 2C receptor.
Despite chronically elevated food intake, young adult mutants exhibit neither elevated adiposity
nor altered glucose or fat homeostasis. However, obesity subsequently develops after 6 ... Cited by 38 - Related articles - BL Direct - All 5 versions
JA McQuade, SC Benoit, M Xu, SC Woods, RJ … - Behavioural brain …, 2004 - Elsevier Dopamine (DA) signaling has been implicated in the control of energy balance and ingestive
behavior. In the present study, we sought to characterize body weight, body fat and food intake
regulation in a mouse with a targeted disruption of the dopamine-3 receptor gene (Drd3). ... Cited by 11 - Related articles - All 3 versions
S Uehara, M Tsuchida, T Kanno, M Sasaki, M … - International journal of …, 2003 - ncbi.nlm.nih.gov We previously generated a strain of transgenic mice carrying the human renin gene,
hRN8-12, in the background of C57BL/6j. In this study, we discovered that hRN8-12 male
mice, but not females, developed obesity starting at 15 weeks of age. The body weight of ... Cited by 8 - Related articles - BL Direct - All 5 versions
CYSHSBJ HK, KEJOWJJ SY, HJSL MJ - Experimental Animals - 万方数据资源系统 Mice carrying a mutation in the first intron of Unc5h3 were accidentally produced by transgenic
insertion and characterized for their homozygous mutant phenotypes. Morphological and histological
analysis revealed cerebellar and midbrain abnormalities, which are similar to the ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►endojournals.org DD Lam, MJ Przydzial, SH Ridley, GSH Yeo, JJ … - Endocrinology, 2008 - Endocrine Soc The neurotransmitter serotonin (5-hydroxytryptamine) is a well-established modulator of energy
balance. Both pharmacological and genetic evidence implicate the serotonin 2C receptor
(5-HT 2C R) as a critical receptor mediator of serotonin's effects on ingestive behavior. ... Cited by 27 - Related articles - BL Direct - All 7 versions
- ►physiology.org JT Kero, E Savontaus, M Mikola, U … - American Journal of …, 2003 - Am Physiological Soc Transgenic (TG) female mice, expressing a chimeric bovine luteinizing hormone (LH)
-subunit/human chorionic gonadotropin -subunit COOH-terminal extension (bLH -CTP)
gene, produce high levels of circulating LH and serve as a model for functional ovarian ... Cited by 13 - Related articles - BL Direct - All 5 versions
L Westberg, J Bah, M Rastam, C Gillberg, E … - …, 2002 - muse.lib.nchu.edu.tw Receptors of the 5-HT2C subtype are assumed to be involved in the influence of serotonin on
food intake. A polymorphism in the coding region of the gene for this receptor, resulting in a cysteine
to serine substitution, has been reported. Fifty- seven somatically healthy teenage girls ... Cited by 50 - Related articles - View as HTML - All 9 versions
A Hayashi, M Suzuki, M Sasamata, K … - Journal of Pharmacy and …, 2004 - ingentaconnect.com JPP 2004, 56: 1551–1556 ß 2004 The Authors Received 6 June, 2004 Accepted 24 August,
2004 DOI 10.1211/0022357044841 ISSN 0022-3573 ... Institute for Drug Discovery
Research, Yamanouchi Pharmaceutical Co., Ltd, 21 Miyukigaoka, Tsukuba, Ibaraki 305- ... Cited by 5 - Related articles - BL Direct - All 4 versions
T Masaki, S Chiba, T Yasuda, H Noguchi, T Kakuma, T … - Diabetes, 2004 - Am Diabetes Assoc Histamine H 1 receptors (H 1 -Rs) are found in peripheral tissues and in regions of the hypothalamus
that are concerned with regulating body composition. In the present study, we investigated the
detailed mechanisms of histamine H 1 -Rs in the development of obesity. Histamine H 1 ... Cited by 51 - Related articles - BL Direct - All 6 versions
[CITATION] Leptin-insensitive hyperphagia and type 2 diabetes in mice with a mutated …
