- ►diabetesjournals.org T Pearson, TG Markees, LS Wicker, DV Serreze, LB … - Diabetes, 2003 - Am Diabetes Assoc The loss of self-tolerance leading to autoimmune type 1 diabetes in the NOD mouse model involves at
least 19 genetic loci. In addition to their genetic defects in self-tolerance, NOD mice resist
peripheral transplantation ... Cited by 21 - Related articles - BL Direct - All 6 versions
[CITATION] The NOD mouse model of insulin dependent diabetes: as good as it gets
- ►jimmunol.org T Pearson, TG Markees, DV Serreze, MA … - The Journal of …, 2003 - Am Assoc Immnol Curing type 1 diabetes by islet transplantation requires overcoming both allorejection and recurrent
autoimmunity. This has been achieved with systemic immunosuppression, but tolerance induction would
be preferable. Most islet ... Cited by 30 - Related articles - BL Direct - All 7 versions
T Pearson, P Weiser, TG Markees, DV Serreze, LS … - Diabetes, 2004 - Am Diabetes Assoc NOD mice develop type 1 autoimmune diabetes and exhibit genetically dominant resistance to
transplantation tolerance induction. These two phenotypes are genetically separable. Costimulation
blockade fails to prolong skin ... Cited by 16 - Related articles - BL Direct - All 6 versions
T Pearson, TG Markees, DV Serreze, MA … - ANNALS-NEW …, 2003 - interscience.wiley.com Abstract: Recent advances in islet transplantation have enabled physicians to cure type 1 autoimmune
diabetes, but at the cost of lifelong immunosuppression with its attendant side effects and
long-term health risks. To ... Cited by 11 - Related articles - BL Direct - All 7 versions
- ►jimmunol.org NN Iwakoshi, TG Markees, N Turgeon, T … - The Journal of …, 2001 - Am Assoc Immnol Treatment of mice with a single donor-specific transfusion plus a brief course of anti-CD154 mAb
uniformly induces donor-specific transplantation tolerance characterized by the deletion of
alloreactive CD8 + T cells. ... Cited by 62 - Related articles - BL Direct - All 5 versions
TG Markees, DV Serreze, NE Phillips, CH … - DIABETES-NEW …, 1999 - Am Diabetes Assoc A protocol consisting of a single donor-specific trans- fusion (DST) plus a brief course of
anti-CD154 mono- clonal antibody (anti-CD40 ligand mAb) induces per- manent islet allograft survival
in chemically diabetic mice, but ... Cited by 79 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org RD Molano, T Berney, H Li, P Cattan, A Pileggi, C … - Diabetes, 2001 - Am Diabetes Assoc Allorejection and recurrence of autoimmunity are the major barriers to transplantation of islets of
Langerhans for the cure of type 1 diabetes in humans. CD40-CD154 (CD40 ligand) interaction blockade
by the use of anti-CD154 monoclonal ... Cited by 76 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org EJ Gordon, LS Wicker, LB Peterson, DV Serreze, TG … - Diabetes, 2005 - Am Diabetes Assoc Costimulation blockade induces prolonged rat islet and skin xenograft survival in C57BL/6 mice.
Nonobese diabetic (NOD) mice, which are used to model human autoimmune diabetes, are resistant to
costimulation blockade-induced ... Cited by 6 - Related articles - All 7 versions
TPTGM Linda - 糖尿病学杂志, 2003 - journal.shouxi.net The loss of self-tolerance leading to autoimmune type 1 diabetes in the NOD mouse model involves at
least 19 genetic loci. In addition to their genetic defects in self-tolerance, NOD mice resist
peripheral transplantation ... Related articles - Cached
