- ►glucagon.com [PDF] DKY Trinh, K Zhang, M Hossain, PL Brubaker, … - Diabetes, 2003 - Am Diabetes Assoc The proglucagon gene encodes pancreatic glucagon and the glucagon-like peptides,
which exert diverse effects on nutrient absorption and assimilation. The
therapeutic potential of glucagon-like peptide-1 (GLP-1) has fostered ... Cited by 16 - Related articles - BL Direct - All 6 versions
ME Hill, SL Asa, DJ Drucker - Molecular Endocrinology, 1999 - Endocrine Soc The primary function of islet A cells is the synthesis and secretion of
glucagon, an essential hormonal regulator of glucose homeostasis. The
proglucagon gene is also expressed in enteroendocrine L cells of the ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►endojournals.org G Flock, X Cao, DJ Drucker - Endocrinology, 2005 - Endocrine Soc Pdx-1 plays a key role in the development of the pancreas and the control of
islet gene transcription and has also been proposed as a dominant regulator of
the - vs. ß-cell phenotype via extinction of proglucagon expression. To ... Cited by 7 - Related articles - All 7 versions
- ►jbc.org CM McKinnon, MA Ravier, GA Rutter - Journal of Biological Chemistry, 2006 - ASBMB Forkhead/winged helix box gene, group O-1 (FoxO1) is a member of a family of
nuclear transcription factors regulated by insulin-dependent phosphorylation and
implicated in the development of the endocrine pancreas. We show here ... Cited by 9 - Related articles - All 5 versions
- ►physiology.org M Nian, DJ Drucker, D Irwin - American Journal of Physiology- Gastrointestinal and …, 1999 - Am Physiological Soc A single mammalian proglucagon gene is expressed in the brain, islets, and
intestinal enteroendocrine cells, which gives rise to a unique profile of
proglucagon-derived peptides (PGDPs) in each tissue. The biological ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►physiology.org M Nian, J Gu, DM Irwin, DJ Drucker - … Journal of Physiology- Regulatory, Integrative and …, 2002 - Am Physiological Soc The glucagon-like peptides (GLPs) are synthesized and secreted in a
nutrient-dependent manner in rodents; however, the factors regulating human
GLP-1 and GLP-2 biosynthesis remain unclear. To understand how nutrients ... Cited by 21 - Related articles - BL Direct - All 6 versions
- ►nih.gov LI Jepeal, MO Boylan, M Michael Wolfe - Molecular and cellular endocrinology, 2008 - Elsevier A thorough examination of glucose-dependent insulinotropic polypeptide (GIP)
expression has been hampered by difficulty in isolating widely dispersed,
GIP-producing enteroendocrine K-cells. To elucidate the molecular ... Cited by 3 - Related articles - All 3 versions
- ►endocrinology-journals.org T Jin - Journal of Endocrinology, 2008 - Soc Endocrinology The proglucagon gene (gcg) encodes a number of peptide hormones that are of
cell-type specifically expressed in the pancreatic islets, the distal ileum and
the large intestine, as well as certain brain neuronal cells. These ... Cited by 3 - Related articles - All 8 versions
T Jin, DJ Drucker - Molecular Endocrinology, 1995 - Endocrine Soc The gene encoding proglucagon is expressed in the A cells of the pancreas,
selected neurons of the central nervous system, and enteroendocrine cells of the
small and large intestine. A single proglucagon mRNA transcript, derived ... Cited by 34 - Related articles - BL Direct - All 4 versions
