C Weigert, K Brodbeck, FC Brosius III, M … - Diabetes, 2003 - Am Diabetes Assoc Recent experimental work indicates that the hyperglycemia-induced increase in
mesangial matrix production, which is a hallmark in the development of diabetic
nephropathy, is mediated by increased expression of GLUT1. Mesangial cells ... Cited by 36 - Related articles - BL Direct - All 4 versions
K Inoki, M Haneda, S Maeda, D Koya, R … - Kidney international, 1999 - nature.com To prove this hypothesis, we examined the effect of TGF- 1 on glucose uptake,
the first step of glucose metabolism, in mesangial cells. 2-Deoxy-D-glucose
(2DOG) uptake and the expression of GLUT1 were measured in mesangial cells ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] CW Heilig, JI Kreisberg, S Freytag, T Murakami … - American Journal of Physiology- Renal Physiology, 2001 - Am Physiological Soc 31 articles, 17 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/280/4/F657#BIBL ... 7 other
HighWire hosted articles, the first 5 are: This article has been cited by Cited by 28 - Related articles - BL Direct - All 3 versions
CW Heilig, Y Liu, RL England, SO Freytag, JD … - Diabetes, 1997 - Am Diabetes Assoc The complications of diabetes arise in part from abnormally high cellular
glucose uptake and metabolism. To determine whether altered glucose transporter
expression may be involved in the pathogenesis of diabetic nephropathy, we ... Cited by 91 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org L Gnudi, GC Viberti, L Raij, V Rodriguez, D … - Hypertension, 2003 - Am Heart Assoc Mesangial matrix deposition is the hallmark of hypertensive and diabetic
glomerulopathy. At similar levels of systemic hypertension, Dahl salt-sensitive
but not spontaneously hypertensive rats (SHR) develop glomerular ... Cited by 42 - Related articles - BL Direct - All 9 versions
- ►iovs.org R Fernandes, K Suzuki, AK Kumagai - Investigative ophthalmology & visual science, 2003 - ARVO 1 From the Department of Internal Medicine and the 2 Juvenile Diabetes Research
Foundation (JRDF) Center for Complications in Diabetes, University of Michigan
Medical School, Ann Arbor, Michigan; the 3 Biomedical Institute for ... Cited by 19 - Related articles - BL Direct - All 4 versions
A Nose, Y Mori, Y Uchiyama-Tanaka, N … - Hypertension research: official journal of the Japanese …, 2003 - ncbi.nlm.nih.gov In the development of diabetic nephropathy, angiotensin (Ang) II is thought to
exert numerous actions on the glomerulus, and especially on the mesangium.
However, the role(s) played by Ang II in the glucose metabolism per se in ... Cited by 34 - Related articles - BL Direct
- ►endojournals.org H Schmid, M Bertoluci, TM Coimbra - Endocrinology, 2008 - Endocrine Soc Diabetic nephropathy is one of the major causes of end-stage renal disease,
affecting approximately one third of patients with type 1 and a significant
number of patients with type 2 diabetes (1). Both hyperglycemia and ... Cited by 2 - Related articles - BL Direct - All 2 versions
- ►nih.gov [PDF] CW Heilig, LA Concepcion, BL Riser, SO … - Journal of Clinical Investigation, 1995 - pubmedcentral.nih.gov An environment of high glucose concentration stimulates the synthesis of
extracellular matrix (ECM) in mesangial cell (MC) cultures. This may result from
a similar increase in intracellular glucose concentration. We theorized ... Cited by 149 - Related articles - BL Direct - All 8 versions
- ►asnjournals.org C WEIGERT, U SAUER, K BRODBECK, A … - Journal of the American Society of Nephrology, 2000 - Am Soc Nephrol Abstract. Hyperglycemia-induced overproduction of the prosclerotic cytokine
transforming growth factor-ß1 (TGF-ß1) has been implicated in the pathogenesis
of diabetic nephropathy. Because high glucose and phorbol esters (PMA) ... Cited by 112 - Related articles - BL Direct - All 5 versions
