K Ekberg, T Brismar, BL Johansson, B Jonsson … - Diabetes, 2003 - Am Diabetes Assoc Studies have demonstrated that proinsulin C-peptide stimulates the activities of
Na + ,K + -ATPase and endothelial nitric oxide synthase, both of which are
enzyme systems of importance for nerve function and known to be deficient ... Cited by 106 - Related articles - BL Direct - All 5 versions
MA Cotter, K Ekberg, J Wahren, NE Cameron - Diabetes, 2003 - Am Diabetes Assoc Proinsulin C-peptide treatment can partially prevent nerve dysfunction in type 1
diabetic rats and patients. This could be due to a direct action on nerve fibers
or via vascular mechanisms as C-peptide stimulates the nitric oxide (NO) ... Cited by 51 - Related articles - BL Direct - All 4 versions
G Grunberger, X Qiang, Z Li, ST Mathews, D … - Diabetologia, 2001 - Springer C-peptide is a 31-amino acid peptide that is derived from proinsulin during
biosynthesis of insulin [1]. Beneficial effects of C-peptide replacement, along
with insulin, in C-peptide deficient states have been documented [2±5]. In ... Cited by 76 - Related articles - BL Direct - All 4 versions
BL Johansson, K Borg, E Fernqvist-Forbes, A … - Diabetic Medicine, 2000 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 102 - Related articles - BL Direct - All 6 versions
- ►kappa.ro [PDF] AAF Sima, W Zhang, K Sugimoto, D Henry, Z … - Diabetologia, 2001 - Springer Diabetic polyneuropathy (DPN) occurs in Type I (in- sulin-dependent) diabetes
mellitus and Type II (non- insulin-dependent) diabetes mellitus and is believed ... C-peptide prevents and improves chronic Type I diabetic Cited by 87 - Related articles - BL Direct - All 6 versions
Z Li, W Zhang, A Sima - Diabetes/Metabolism Reviews - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 67 - Related articles - BL Direct - All 4 versions
BL Johansson, K Borg, E Fernqvist-Forbes, T … - Diabetologia, 1996 - Springer Summary In order to determine the possible influ- ence of C-peptide on nerve
function, 12 insulin-de- pendent diabetic (IDDM) patients with symptoms of
diabetic polyneuropathy were studied twice under euglycaemic conditions. ... Cited by 94 - Related articles - BL Direct - All 4 versions
AAF Sima - eid, 2003 - informahealthcare.com 1. Introduction 2. The natural history of diabetic polyneuropathy in Type 1 and
Type 2 diabetes 3. Pathogenetic considerations in Type 1 and Type 2 diabetic
polyneuropathy 4. The effect of C-peptide on experimental Type 1 diabetic ... Cited by 45 - Related articles - All 4 versions
Y Ohtomo, A Aperia, B Sahlgren, BL … - Diabetologia, 1996 - Springer Summary This study was performed in order to test the hypothesis that the
connecting peptide of pro- insulin, C-peptide, might in itself possess
biological ac- tivity. Renal tubular Na +, K +-ATPase, which is a well- ... Cited by 113 - Related articles - BL Direct - All 3 versions
CR Pierson, W Zhang, AAF Sima - Journal of Neuropathology & Experimental Neurology, 2003 - journals.lww.com We recently reported that early gene responses and expression of cytoskeletal
proteins are perturbed in regenerating nerve in type 1 insulinopenic diabetes
but not in type 2 hyperinsulinemic diabetes. We hypothesized that these ... Cited by 40 - Related articles - BL Direct - All 4 versions
