A Kubaszek, J Pihlajamäki, K Punnonen, P … - Diabetes, 2003 - Am Diabetes Assoc Interleukin-6 (IL-6) is a pleiotropic cytokine expressed in many tissues. IL-6
null mice show low energy expenditure, but the effect of the variants of the
IL-6 gene on energy expenditure has not been previously studied in humans. ... Cited by 92 - Related articles - BL Direct - All 4 versions
B Vozarova, JM Fernández-Real, WC Knowler, … - Human genetics, 2003 - Springer Abstract Chronic low-grade activation of the immune system may play a role in
the pathogenesis of type-2 dia- betes mellitus (T2DM). Interleukin-6 (IL6), a
powerful inducer of hepatic acute phase response, has been impli- cated in ... Cited by 105 - Related articles - BL Direct - All 4 versions
AKJ Pihlajamä - 糖尿病学杂志, 2003 - journal.shouxi.net Interleukin-6 (IL-6) is a pleiotropic cytokine expressed in many tissues. IL-6
null mice show low energy expenditure, but the effect of the variants of the
IL-6 gene on energy expenditure has not been previously studied in humans. ... Related articles - Cached
- ►endojournals.org [PDF] M Mohlig, H Boeing, J Spranger, M Osterhoff, … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Increased levels of IL-6 add further risk to the impact of obe- sity in respect
to the development of type 2 diabetes mellitus (T2DM). A C-174G polymorphism
within the IL-6 promoter region was shown to influence transcription rate ... Cited by 47 - Related articles - BL Direct - All 4 versions
JM Fernández-Real, M Broch, J Vendrell, C … - Diabetes, 2000 - Am Diabetes Assoc Type 2 diabetes and the insulin resistance syndrome have been hypothesized to
constitute manifestations of an ongoing acute-phase response. We aimed to study
an interleukin-6 (IL-6) gene polymorphism in relation to insulin ... Cited by 183 - Related articles - BL Direct - All 3 versions
I Wernstedt, AL Eriksson, A Berndtsson, J … - International Journal of Obesity, 2004 - nature.com OBJECTIVE: Human body fat mass is to a large extent genetically determined, but
little is known about the susceptibility genes for common obesity. Interleukin-6
(IL-6) suppresses body fat mass in rodents, and IL-6 treatment increases ... Cited by 64 - Related articles - BL Direct - All 3 versions
- ►endojournals.org [PDF] T Illig, F Bongardt, A Schopfer, S Muller- … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Elevated blood concentrations of IL-6 have been shown to predict type 2
diabetes. Because the impact of IL-6 gene poly- morphisms on diabetes status,
parameters of the metabolic syndrome, and low-grade systemic inflammation ... Cited by 47 - Related articles - BL Direct - All 4 versions
JW Stephens, SJ Hurel, JA Cooper, J Acharya … - Molecular genetics and metabolism, 2004 - Elsevier Circulating levels of interleukin-6 (IL-6) are raised in insulin resistant
states such as obesity, impaired glucose tolerance (IGT), and type 2 diabetes
mellitus (T2DM). Growing evidence suggests that IL-6 is not only produced ... Cited by 33 - Related articles - All 4 versions
A Kubaszek, J Pihlajamäki, V Komarovski, V … - Diabetes, 2003 - Am Diabetes Assoc High levels of cytokines are risk factors for type 2 diabetes. Therefore, we
investigated whether the promoter polymorphisms of the tumor necrosis factor-α
(TNF-α; G-308A) and interleukin 6 (IL-6; C-174G) genes predict the ... Cited by 104 - Related articles - BL Direct - All 5 versions
