H Osawa, H Onuma, A Murakami, M Ochi, T … - Diabetes, 2003 - Am Diabetes Assoc FOXC2, a forkhead/winged helix transcription factor, represents a promising
candidate gene for type 2 diabetes since transgenic mice that specifically
overexpress this gene in adipocytes are lean and insulin sensitive. To ... Cited by 17 - Related articles - BL Direct - All 5 versions
P Kovacs, A Lehn-Stefan, M Stumvoll, C … - Diabetes, 2003 - Am Diabetes Assoc FOXC2 is a winged helix gene that has been shown to counteract obesity,
hypertriglyceridemia, and diet-induced insulin resistance in rodents. Therefore,
FOXC2 was analyzed as a candidate gene for susceptibility to type 2 ... Cited by 21 - Related articles - BL Direct - All 5 versions
… Murakami, MOTNK Kato, ISYFJ Ohashi, H … - 糖尿病学杂志, 2003 - journal.shouxi.net FOXC2, a forkhead/winged helix transcription factor, represents a promising
candidate gene for type 2 diabetes since transgenic mice that specifically
overexpress this gene in adipocytes are lean and insulin sensitive. To ... Related articles - Cached
M Ridderstråle, E Carlsson, M Klannemark, A … - Diabetes, 2002 - Am Diabetes Assoc The human transcription factor FOXC2 has recently been shown to protect against
diet-induced insulin resistance in transgenic mice. We investigated the
expression of FOXC2 in fat and muscle and performed a genetic analysis in ... Cited by 36 - Related articles - BL Direct - All 6 versions
K Yanagisawa, L Hingstrup Larsen, G … - Diabetologia, 2003 - Springer Aims/hypothesis. The transcription factor FOXC2 plays a key role in adipocyte
differentiation and the FOXC2 gene is a candidate gene for Type 2 diabetes,
obesity and dyslipidaemia. We investigated whether the FOXC2 -512C>T ... Cited by 18 - Related articles - BL Direct - All 3 versions
H Osawa, H Onuma, A Murakami, M Ochi, T … - Biochemical and Biophysical Research …, 2001 - Elsevier It has recently been shown that the A/A genotype at g.−23 of the insulin gene
correlates with impaired insulin secretion in response to body weight gain in
subjects of European descent. To examine whether there are single ... Cited by 8 - Related articles - BL Direct - All 5 versions
E Carlsson, L Groop, M Ridderstråle - International Journal of Obesity, 2004 - nature.com FOXC2 –512C>T allele and genotype distribution did not differ between patients
with type 2 diabetes and control subjects, but the C/C genotype was associated
with increased body mass index (BMI, kg/m 2 ) (P a =0.03) among type 2 ... Cited by 12 - Related articles - All 3 versions
A Fritsche, F Machicao, H Staiger, HU Häring … - Diabetologia, 2004 - Springer To the Editor: A recent paper reported an association between the −512C>T
promoter polymorphism in the forkhead box C2 (FOXC2) gene and increased serum
C-peptide and hyper- triglyceridaemia in normal-glucose-tolerant subjects ... Cited by 3 - Related articles - BL Direct - All 4 versions
[CITATION] FOXC2 mRNA expression and a 50 untranslated region polymorphism of the gene are …
R Sano, T Miki, Y Suzuki, F Shimada, M Taira … - Diabetes research and clinical practice, 2001 - Elsevier We screened for mutations in the gene of insulin–sensitive phosphodiesterase
3B (PDE3B), which regulates antilipolytic actions of insulin via reduction of
intracellular cyclic AMP levels, in Japanese patients with type 2 diabetes ... Cited by 6 - Related articles - All 8 versions