- ►diabetesjournals.org H Pilegaard, B Saltin, PD Neufer - Diabetes, 2003 - Am Diabetes Assoc During short-term fasting, substrate utilization in skeletal muscle shifts from predominantly carbohydrate
to fat as a means of conserving glucose. To examine the potential influence of short-term fasting
and refeeding on transcriptional regulation in skeletal muscle, muscle biopsies were ... Cited by 70 - Related articles - BL Direct - All 4 versions
- ►physiology.org SJ Peters, RA Harris, P Wu, TL Pehleman, … - American Journal of …, 2001 - Am Physiological Soc The increase in skeletal muscle pyruvate dehydrogenase kinase (PDK) activity was measured
in skeletal muscle of six healthy males after a eucaloric high-fat/low-carbohydrate (HF/LC; 5%
carbohydrate, 73% fat, and 22% protein of total energy intake) diet compared with a ... Cited by 68 - Related articles - BL Direct - All 6 versions
- ►physiology.org LL Spriet, RJ Tunstall, MJ Watt, KA Mehan … - Journal of Applied …, 2004 - Am Physiological Soc Fasting forces adaptive changes in whole body and skeletal muscle metabolism that increase
fat oxidation and decrease the oxidation of carbohydrate. We tested the hypothesis that 40 h
of fasting would decrease pyruvate dehydrogenase (PDH) activity and increase PDH ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►physiology.org H Pilegaard, GA Ordway, B Saltin, PD … - American Journal of …, 2000 - Am Physiological Soc Exercise training elicits a number of adaptive changes in skeletal muscle that result in an improved
metabolic efficiency. The molecular mechanisms mediating the cellular adaptations to exercise
training in human skeletal muscle are unknown. To test the hypothesis that recovery from ... Cited by 251 - Related articles - BL Direct - All 4 versions
H Pilegaard, C Keller, A Steensberg, J Wulff … - The Journal of …, 2002 - Physiological Soc Transcription of metabolic genes is transiently induced during recovery from exercise in skeletal
muscle of humans. To determine whether pre-exercise muscle glycogen content influences the
magnitude and/or duration of this adaptive response, six male subjects performed one- ... Cited by 85 - Related articles - BL Direct - All 8 versions
- ►physiology.org EA Turvey, GJF Heigenhauser, M Parolin … - Journal of Applied …, 2005 - Am Physiological Soc We tested the hypothesis that a high-fat diet (75% fat; 5% carbohydrates; 20% protein), for which
15% of the fat content was substituted with n-3 fatty acids, would not exhibit the diet-induced
increase in pyruvate dehydrogenase kinase (PDK) activity, which is normally observed in ... Cited by 9 - Related articles - All 6 versions
- ►physiology.org AL Hildebrandt, PD Neufer - American Journal of Physiology- …, 2000 - Am Physiological Soc Fasting elicits a progressive increase in lipid metabolism within skeletal muscle. To determine
the effects of fasting on the transcriptional regulation of genes important for metabolic control
in skeletal muscle composed of different fiber types, nuclei from control and fasted (24 ... Cited by 68 - Related articles - BL Direct - All 4 versions
- ►physiology.org AL Hildebrandt, H Pilegaard, PD … - American Journal of …, 2003 - Am Physiological Soc Cellular adaptations to endurance training are influenced by the intensity and duration of
exercise. To examine the impact of exercise intensity and duration on the acute transcriptional
regulation of metabolic genes in red (RG) and white (WG) gastrocnemius muscle, rats ... Cited by 55 - Related articles - BL Direct - All 4 versions
H Pilegaard, T Osada, LT Andersen, JW Helge, B Saltin … - Metabolism, 2005 - Elsevier In skeletal muscle of humans, transcription of several metabolic genes is transiently induced
during recovery from exercise when no food is consumed. To determine the potential influence
of substrate availability on the transcriptional regulation of metabolic genes during ... Cited by 34 - Related articles - All 11 versions
G Ward, J Sutton, N Jones, C Toews - Clinical Science, 1982 - cs.portlandpress.com 1. The activity of pyruvate dehydrogenase in its active and inactive forms was measured in biopsy
samples obtained from the vastus lateralis muscle of healthy subjects before and after
exercise. 2. At rest, 40 +/- 4% (mean +/- SEM) of the enzyme was in the active form. 3. ... Cited by 13 - Related articles - Cached - All 8 versions
