H Lan, ME Rabaglia, JP Stoehr, ST Nadler, KL … - Diabetes, 2003 - Am Diabetes Assoc Obesity is a strong risk factor for the development of type 2 diabetes. We have
previously reported that in adipose tissue of obese (ob/ob) mice, the expression
of adipogenic genes is decreased. When made genetically obese, the BTBR ... Cited by 77 - Related articles - BL Direct - All 15 versions
JP Stoehr, ST Nadler, KL Schueler, ME … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc Nonlinear interactions between obesity and genetic risk factors are thought to
determine susceptibility to type 2 diabetes. We used genetic obesity as a tool
to uncover latent differences in diabetes susceptibility between two mouse ... Cited by 74 - Related articles - BL Direct - All 15 versions
C Colombo, M Haluzik, JJ Cutson, KR Dietz, … - Journal of Biological Chemistry, 2003 - ASBMB The metabolic phenotype of the A-ZIP/F-1 (AZIP) lipoatrophic mouse is different
depending on its genetic background. On both the FVB/N (FVB) and C57BL/6J (B6)
backgrounds, AZIP mice have a similarly severe lack of white adipose tissue ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org T Ranheim, C Dumke, KL Schueler, GD Cartee … - Arteriosclerosis, thrombosis, and vascular biology, 1997 - Am Heart Assoc Abstract Insulin resistance is a common syndrome that often precedes the
development of noninsulin-dependent diabetes mellitus (NIDDM). Both diet and
genetic factors are associated with insulin resistance. BTBR and C57BL/6J ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►genetics.org H Lan, JP Stoehr, ST Nadler, KL Schueler, BS … - Genetics, 2003 - Genetics Soc America The advent of sophisticated genomic techniques for gene mapping and microarray
analysis has provided opportunities to map mRNA abundance to quantitative trait
loci (QTL) throughout the genome. Unfortunately, simple mapping of each ... Cited by 48 - Related articles - BL Direct - All 14 versions
- ►nutrition.org ST Nadler, AD Attie - Journal of Nutrition, 2001 - Am Soc Nutrition Type 2 diabetes mellitus is an increasingly common disorder of carbohydrate and
lipid metabolism. Approximately 16 million individuals in the United States have
diabetes, and 800,000 new cases are identified each year. Two important ... Cited by 74 - Related articles - BL Direct - All 6 versions
J Xu, WN Lee, J Phan, MF Saad, K Reue, IJ … - Diabetes, 2006 - Am Diabetes Assoc Fatty liver is a common feature of both obesity and lipodystrophy, reflecting
compromised adipose tissue function. The lipin-deficient fatty liver dystrophy
(fld) mouse is an exception, as there is lipodystrophy without a fatty ... Cited by 14 - Related articles - BL Direct - All 7 versions
- ►wisc.edu [PDF] SM Clee, ST Nadler, AD Attie - American journal of therapeutics, 2005 - journals.lww.com The BTBR mouse strain harbors alleles promoting insulin resistance. When made
genetically obese (ob/ob), these mice develop severe type 2 diabetes (fasting
glucose .400 mg/dL). By contrast, C57BL/6 ob/ob mice are able to compensate ... Cited by 16 - Related articles - BL Direct - All 7 versions
- ►nih.gov [PDF] ST Nadler, JP Stoehr, KL Schueler, G … - Proceedings of the National Academy of Sciences, 2000 - National Acad Sciences Obesity is strongly correlated with type 2 diabetes mellitus, a common disorder
of glucose and lipid metabolism. Although adipocytes are critical in obesity,
their role in diabetes has only recently been appreciated. We conducted ... Cited by 230 - Related articles - BL Direct - All 16 versions
