X Geng, L Li, S Watkins, PD Robbins, P Drain - Diabetes, 2003 - Am Diabetes Assoc With ATP sites on K ir 6.2 that inhibit activity and ADP sites on SUR1 that
antagonize the inhibition, ATP-sensitive potassium channels (K ATP channels) are
designed as exquisite sensors of adenine nucleotide levels that signal ... Cited by 63 - Related articles - BL Direct - All 4 versions
X Geng, L Li, S Watkins, PD Robbins, P Drain - DIABETES, 2003 - Am Diabetes Assoc With ATP sites on K ir 6.2 that inhibit activity and ADP sites on SUR1 that
antagonize the inhibition, ATP- sensitive potassium channels (K ATP channels)
are de- signed as exquisite sensors of adenine nucleotide levels that ... Related articles
A Varadi, A Grant, M McCormack, T Nicolson, … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1567–1577 DOI 10.1007/s00125-006-0257-9 ARTICLE
A. Varadi . A. Grant . M. McCormack . T. Nicolson . M. Magistri . ... Cited by 18 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org F Kamp, N Kizilbash, BE Corkey, PO Berggren … - Diabetes, 2003 - Am Diabetes Assoc Because sulfonylureas directly activate the exocytotic machinery, we were
interested in the extent to which these compounds penetrate the β-cell plasma
membrane and the underlying molecular mechanism(s). We now provide evidence ... Cited by 16 - Related articles - BL Direct - All 4 versions
SE Ozanne, PC Guest, JC Hutton, CN Hales - Diabetologia, 1995 - Springer Summary Sulphonylureas stimulate insulin secretion by binding to a receptor in
the pancreatic beta-cell plasma membrane resulting in inhibition of ATP-sen-
sitive K + channels, membrane depolarization and thus influx of Ca 2§ ... Cited by 57 - Related articles - BL Direct - All 4 versions
JL Carpentier, F Sawano, M Ravazzola, WJ … - Diabetologia, 1986 - Springer Hypoglycaemic sulfonylureas stimulate insulin release. Although the molecular
determinants of their insulino- tropic action remain to be fully elucidated, it
is currently assumed that these drugs bind to the B-cell plasma membrane ... Cited by 48 - Related articles - All 3 versions
E Renström, S Barg, F Thévenod, P Rorsman - Diabetes, 2002 - Am Diabetes Assoc Several reports indicate that hypoglycemic sulfonylureas augment Ca 2+
-dependent insulin secretion via mechanisms other than inhibition of the
ATP-sensitive K + channel. The effect involves a 65-kd protein in the ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org M Nakazaki, A Crane, M Hu, V Seghers, S … - Diabetes, 2002 - Am Diabetes Assoc Whereas the loss of ATP-sensitive K + channel (K ATP channel) activity in human
pancreatic β-cells causes severe hypoglycemia in certain forms of
hyperinsulinemic hypoglycemia, similar channel loss in sulfonylurea ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►jbc.org M Nenquin, A Szollosi, L Aguilar-Bryan, J … - Journal of Biological Chemistry, 2004 - ASBMB In normal -cells glucose induces insulin secretion by activating both a
triggering pathway (closure of K ATP channels, depolarization, and rise in
cytosolic [Ca 2+ ] i ) and an amplifying pathway (augmentation of Ca 2+ ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►rupress.org L Eliasson, X Ma, E Renstrom, S Barg, PO … - Journal of General Physiology, 2003 - jgp.rupress.org Measurements of membrane capacitance were applied to dissect the cellular
mechanisms underlying PKA-dependent and -independent stimulation of insulin
secretion by cyclic AMP. Whereas the PKA-independent ... Cited by 113 - Related articles - BL Direct - All 5 versions
