G Ye, NS Metreveli, J Ren, PN Epstein - Diabetes, 2003 - Am Diabetes Assoc Many individuals with diabetes experience impaired cardiac contractility that
cannot be explained by hypertension and atherosclerosis. This cardiomyopathy may
be due to either organ-based damage, such as fibrosis, or to direct damage ... Cited by 105 - Related articles - BL Direct - All 5 versions
Q Liang, EC Carlson, RV Donthi, PM Kralik, X … - Diabetes, 2002 - Am Diabetes Assoc Many diabetic patients suffer from cardiomyopathy, even in the absence of
vascular disease. This diabetic cardiomyopathy predisposes patients to heart
failure and mortality from myocardial infarction. Evidence from animal ... Cited by 89 - Related articles - BL Direct - All 4 versions
L Cai, YJ Kang - Cardiovascular Toxicology, 2001 - Springer *Author to whom all correspondence and reprint requests should be addressed: Y.
James Kang, Department of Medicine, University of Louisville School of Medicine,
511 S. Floyd St., MDR 530, Louisville, KY 40202. E-mail: yjkang01@athena. ... Cited by 109 - Related articles - All 3 versions
- ►onlinejacc.org L Cai, Y Wang, G Zhou, T Chen, Y Song, X Li, … - Journal of the American College of Cardiology, 2006 - Elsevier Our previous study showed that cardiac apoptosis as a major early cellular
response to diabetes is induced by hyperglycemia-derived oxidative stress that
activates a mitochondrial cytochrome c-mediated caspase-3 activation ... Cited by 51 - Related articles - BL Direct - All 20 versions
L Cai, J Wang, Y Li, X Sun, L Wang, Z Zhou, … - Diabetes, 2005 - Am Diabetes Assoc The mechanisms of metallothionein prevention of diabetic cardiomyopathy are
largely unknown. The present study was performed to test whether inhibition of
nitrosative damage is involved in metallothionein prevention of diabetic ... Cited by 61 - Related articles - All 5 versions
- ►endocrinology-journals.org [PDF] FL Norby, NS Aberle… - Journal of Endocrinology, 2004 - Soc Endocrinology Diabetic cardiomyopathy is characterized by cardiac dys- function and altered
level/function of insulin-like growth factor I (IGF-I). Both endogenous and
exogenous IGF-I have been shown to effectively alleviate diabetes-induced ... Cited by 29 - Related articles - BL Direct - All 5 versions
G Ye, NS Metreveli, RV Donthi, S Xia, M Xu, … - Diabetes, 2004 - Am Diabetes Assoc Many diabetic patients suffer from a cardiomyopathy that cannot be explained by
poor coronary perfusion. Reactive oxygen species (ROS) have been proposed to
contribute to this cardiomyopathy. Consistent with this we found evidence ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►uwyo.edu [PDF] CX Fang, F Dong, BH Ren, PN Epstein, J Ren - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Insulin resistance is concom- itant with metabolic
syndrome, oxidative stress and cardiac contractile dysfunction. However, the
causal relationship between oxidative stress and cardiac dysfunction is un- ... Cited by 28 - Related articles - BL Direct - All 6 versions
- ►physiology.org FL Norby, LE Wold, J Duan, KK Hintz, J Ren - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Diabetic cardiomyopathy is characterized by impaired ventricular contraction and
altered function of insulin-like growth factor I (IGF-I), a key factor for
cardiac growth and function. Endogenous IGF-I has been shown to alleviate ... Cited by 54 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org L Cai, W Li, G Wang, L Guo, Y Jiang, YJ Kang - Diabetes, 2002 - Am Diabetes Assoc Diabetic cardiomyopathy is related directly to hyperglycemia. Cell death such as
apoptosis plays a critical role in cardiac pathogenesis. Whether hyperglycemia
induces myocardial apoptosis, leading to diabetic cardiomyopathy, remains ... Cited by 172 - Related articles - BL Direct - All 5 versions
