RA Kowluru - Diabetes, 2003 - Am Diabetes Assoc Clinical and experimental studies have shown that reinstitution of good glycemic
control (GC) after a period of poor glycemic control (PC) does not produce
immediate benefits on the progression of retinopathy, and hyperglycemia is ... Cited by 61 - Related articles - BL Direct - All 9 versions
RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ... Cited by 75 - Related articles - BL Direct - All 8 versions
RA Kowluru, S Chakrabarti, S Chen - Acta Diabetologica, 2004 - Springer Abstract Hyperglycemia is one of the major underlying factors in the development
of retinopathy in diabetes. Retinal microvascular cells undergo accelerated
apoptosis before other histopathological changes are detectable in ... Cited by 15 - Related articles - All 4 versions
RA Kowluru, P Koppolu - Free Radical Research, 2002 - informahealthcare.com Apoptosis of retinal endothelial cells and pericytes is postulated to contribute
to the development of retinopathy in diabetes. The goal of this study is to
investigate diabetes- induced activation of retinal caspase-3, an apoptosis ... Cited by 60 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org RA Kowluru, S Odenbach - Diabetes, 2004 - Am Diabetes Assoc Oxidative stress is increased in the retina in diabetes, and it is considered to
play an important role in the development of retinopathy. α-Lipoic acid, a
thiol antioxidant, has been shown to have beneficial effects on ... Cited by 73 - Related articles - BL Direct - All 6 versions
- ►iovs.org RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Mitochondria and cytosol fractions were prepared from retina of rats
with streptozotocin-induced diabetes and from the isolated retinal endothelial
cells and pericytes incubated in 5 or 20 mM glucose medium for up to 10 ... Cited by 52 - Related articles - BL Direct - All 4 versions
- ►chiroonline.net [PDF] RA Kowluru, J Tang, TS Kern - Diabetes, 2001 - Am Diabetes Assoc Antioxidants were administered to diabetic rats and experimentally galactosemic
rats to evaluate the ability of these agents to inhibit the development of
diabetic retinopathy. Alloxan diabetic rats and nondiabetic rats that were ... Cited by 146 - Related articles - BL Direct - All 6 versions
Y Du, MA Smith, CM Miller, TS Kern - Journal of neurochemistry, 2002 - interscience.wiley.com Aminoguanidine inhibits the development of retinopathy in diabetic animals, but
the mechanism remains unclear. Inasmuch as aminoguanidine is a relatively
selective inhibitor of the inducible isoform of nitric oxide synthase ... Cited by 83 - Related articles - BL Direct - All 5 versions
- ►iovs.org RA Kowluru, P Koppolu - Investigative ophthalmology & visual science, 2002 - ARVO METHODS. Experimentally galactosemic rats (normal rats fed a 30% galactose-rich
diet for 2 months) were fed a galactose-free diet for an additional 1 month. At
the end of 3 months, retinas were removed to measure oxidative stress, ... Cited by 12 - Related articles - BL Direct - All 4 versions
RA Kowluru, M Kanwar, A Kennedy - Exp Diabetes Res, 2007 - hindawi.com Aim. Diabetic retinopathy resists reversal after good glycemic control (GC) is
reinitiated, and preexisting damage at the time of intervention is considered as
the major factor in determining the outcome of the GC. This study is to ... Cited by 12 - Related articles - View as HTML - All 13 versions
