T Abiko, A Abiko, AC Clermont, B Shoelson, N … - Diabetes, 2003 - Am Diabetes Assoc Increases in leukostasis/monocyte adhesion to the capillary endothelium
(leukostasis) and decreases in retinal blood flow may be causally associated and
are implicated in the pathogenesis of diabetic retinopathy. In this study, ... Cited by 84 - Related articles - BL Direct - All 9 versions
- ►iovs.org A Nonaka, J Kiryu, A Tsujikawa, K Yamashiro … - Investigative ophthalmology & visual science, 2000 - ARVO PURPOSE. The activity of protein kinase C (PKC), preferentially ß isoform of
PKC, has been shown to be elevated in the diabetic retina. Recently, LY333531, a
specific inhibitor of PKC-ß, has been reported to improve the decrease of ... Cited by 64 - Related articles - BL Direct - All 4 versions
T Yokota, RC Ma, JY Park, K Isshiki, KB … - Diabetes, 2003 - Am Diabetes Assoc Increased expression of endothelin-1 (ET-1) is associated with diabetic
retinopathy and vasculopathy, although the molecular explanation has not been
defined. The effects of high glucose and protein kinase C (PKC) activation ... Cited by 53 - Related articles - BL Direct - All 4 versions
R Chibber, BM Ben-Mahmud, GE Mann, JJ … - Diabetes, 2003 - Am Diabetes Assoc Increased leukocyte-endothelial cell adhesion is a key early event in the
development of retinopathy and atherogenesis in diabetic patients. We recently
reported that raised activity of glycosylating enzyme [β]1,6 ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►iovs.org FC Barouch, K Miyamoto, JR Allport, K Fujita, … - Investigative Ophthalmology & Visual Science, 2000 - ARVO METHODS. Diabetes was induced in Long Evans rats with streptozotocin. The
expression of the surface integrin subunits CD11a, CD11b, and CD18 on rat
neutrophils isolated from peripheral blood was quantitated with flow ... Cited by 116 - Related articles - BL Direct - All 3 versions
- ►jleukbio.org JC Mamputu, G Renier - Journal of leukocyte biology, 2004 - Soc Leukocyte Biology Accumulating evidence indicates a role for advanced glycation end-products
(AGEs) in the development of diabetic retinopathy. In the present study, we
examined the in vitro effect of AGEs on human monocyte adhesion to bovine ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►iovs.org [PDF] SE Bursell, C Takagi, AC Clermont, H Takagi, F … - Investigative ophthalmology & visual science, 1997 - ARVO Purpose. Elevation of diacylglycerol (DAG) and protein kinase C (PKC) levels in
diabetic vascular tissue is associated with abnormalities of retinal and renal
hemodynamics. The object of this study was to determine whether direct ... Cited by 57 - Related articles - BL Direct - All 3 versions
- ►bmj.com [PDF] AP Adamis - British Medical Journal, 2002 - bjo.bmj.com L ast year an ARVO symposium organ- ised by Tim Kern was titled “Is diabetic
retinopathy an inflamma- tory disease?” It is a timely question. chronic
subclinical inflammation may underlie much of the vascular pathology of ... Cited by 96 - Related articles - BL Direct - All 7 versions
N Kato, S Yashima, T Suzuki, Y Nakayama, T … - Journal of Diabetes and its Complications, 2003 - Elsevier It is important to suppress retinal vascular changes for prevention of the onset
and progression of diabetic retinopathy. In the present study, we investigated
the dose–response effect of an aldose reductase (AR) inhibitor, ... Cited by 32 - Related articles - All 8 versions
C Takagi, SE Bursell, YW Lin, H Takagi, E … - Investigative ophthalmology & visual science, 1996 - ARVO PURPOSE: To investigate the role of endogenous endothelin-1 (ET-1) expression
and its interaction with the ETA receptor in the physiologic regulation of
vascular tone as well as in the development of abnormal retinal ... Cited by 104 - Related articles - BL Direct - All 3 versions
