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Scholar Results 1 - 10 of about 101 related to Doublier: Nephrin expression is reduced in human diabetic nephropathy. (0.11 sec) 

Nephrin expression is reduced in human diabetic nephropathy

- diabetesjournals.org
S Doublier, G Salvidio, E Lupia, V … - Diabetes, 2003 - Am Diabetes Assoc
We studied the distribution of nephrin in renal biopsies from 17 patients with
diabetes and nephrotic syndrome (7 type 1 and 10 type 2 diabetes), 6 patients
with diabetes and microalbuminuria (1 type 1 and 5 type 2 diabetes), and 10 ...
Cited by 160 - Related articles - BL Direct - All 6 versions

Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic …


R Langham, D Kelly, A Cox, N Thomson, H … - Diabetologia, 2002 - Springer
Aims/hypothesis. Proteinuria, reflecting increased glomerular permeability to
macromolecules is a char- acteristic feature of diabetic nephropathy. Nephrin, a
1241-residue transmembrane protein is a key compo- nent of the podocyte ...
Cited by 122 - Related articles - BL Direct - All 4 versions

Selective impairment of gene expression and assembly of nephrin in human diabetic …


A Benigni, E Gagliardini, S Tomasoni, M … - Kidney international, 2004 - nature.com
Recent disclosure of podocyte proteins has unraveled previously rather
mysterious mechanisms that govern glomerular perm-selectivity in health and
disease. Here we addressed the role of nephrin, CD2-associated protein ...
Cited by 78 - Related articles - BL Direct - All 4 versions

Nephrin Expression Is Reduced in Human Diabetic Nephropathy


II Angiotensin - Diabetes, 2003 - Am Diabetes Assoc
Page 1. Nephrin Expression Is Reduced in Human Diabetic Nephropathy Evidence
for a Distinct Role for Glycated Albumin and Angiotensin II ...
Related articles

Changes in the expression of nephrin gene and protein in experimental diabetic …


P Aaltonen, P Luimula, E Åström, T Palmen, T … - Laboratory Investigation, 2001 - nature.com
Diabetic nephropathy is a major complication of diabetes leading to thickening
of the glomerular basement membrane, glomerular hypertrophy, mesangial
expansion, and overt renal disease. The pathophysiologic mechanisms of ...
Cited by 98 - Related articles - BL Direct - All 6 versions

Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: …

- oxfordjournals.org
DJ Kelly, P Aaltonen, AJ Cox, JR Rumble, R … - Nephrology Dialysis Transplantation, 2002 - ERA-EDTA
Background. Mutations in the gene coding for the podocyte slit-pore membrane
protein, nephrin, are responsible for the Finnish-type congenital nephrotic
syndrome. The present study sought to examine whether nephrin expression ...
Cited by 96 - Related articles - BL Direct - All 6 versions

Modulation of nephrin in the diabetic kidney: association with systemic hypertension and …


JM Forbes, F Bonnet, LM Russo, WC Burns, Z … - Journal of hypertension, 2002 - journals.lww.com
Page 1. Modulation of nephrin in the diabetic kidney: association with
systemic hypertension and increasing albuminuria Josephine ...
Cited by 69 - Related articles - BL Direct - All 3 versions

Irbesartan normalises the deficiency in glomerular nephrin expression in a model of …


F Bonnet, ME Cooper, H Kawachi, TJ Allen, G … - Diabetologia, 2001 - Springer
[1,2]. The massive proteinuria observed in patients with mutation of the NPHS1
gene suggests a key role for nephrin in the function of the glomerular fil-
tration barrier. Furthermore,different groups have consistently shown a ...
Cited by 182 - Related articles - BL Direct - All 6 versions

Expression of podocyte-associated molecules in acquired human kidney diseases

- asnjournals.org
K Koop, M Eikmans, HJ Baelde, H Kawachi, E … - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol
Proteinuria is an important risk factor for the progression of renal disease,
but the pathophysiologic mechanisms underlying its development are unclear (1).
Ultrafiltration in the glomerulus is accomplished by a fenestrated ...
Cited by 151 - Related articles - BL Direct - All 4 versions

Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients …

- amjpathol.org
S Doublier, V Ruotsalainen, G Salvidio, E … - American Journal of Pathology, 2001 - ASIP
We investigated the distribution of nephrin by immunofluorescence microscopy in
renal biopsies of patients with nephrotic syndrome: 13 with membranous
glomerulonephritis (GN), 10 with minimal change GN, and seven with focal ...
Cited by 161 - Related articles - BL Direct - All 4 versions


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