HJ Woerle, PR Mariuz, C Meyer, RC Reichman, EM … - Diabetes, 2003 - Am Diabetes Assoc The mechanisms responsible for the deterioration in glucose tolerance associated with protease
inhibitor–containing regimens in HIV infection are unclear. Insulin resistance has been implicated
as a major factor, but the affected tissues have not been identified. Furthermore, β-cell ... Cited by 99 - Related articles - BL Direct - All 9 versions
HC Experiments - members.medscape.com Baseline characteristics of the groups did not differ except that the NRTI-naïve subjects had lower
initial body fat. During 12 weeks of treatment, BMI, total body fat, and lean body mass did not
change in either group; viral load decreased by >80% in both groups (P < 0.001) ( Table 2 ). Related articles
PW Hruz, H Murata, H Qiu, M Mueckler - Diabetes, 2002 - Am Diabetes Assoc The use of HIV protease inhibitors (PIs) has been associated with several metabolic
changes, including lipodystrophy, hyperlipidemia, and insulin resistance. The etiology of these
adverse effects remains unknown. PIs have recently been found to cause acute and ... Cited by 76 - Related articles - BL Direct - All 4 versions
JC Koster, MS Remedi, H Qiu, CG Nichols, PW Hruz - Diabetes, 2003 - Am Diabetes Assoc HIV protease inhibitors (PIs) acutely and reversibly inhibit the insulin-responsive glucose transporter
Glut 4, leading to peripheral insulin resistance and impaired glucose tolerance. Minimal modeling
analysis of glucose tolerance tests on PI-treated patients has revealed an impaired ... Cited by 54 - Related articles - BL Direct - All 5 versions
MA Noor, T Seneviratne, FT Aweeka, JC Lo, JM … - Aids, 2002 - journals.lww.com From the From the Department of a Medicine, University of California, the b Metabolism and Endocrine
Sections, San Francisco Department of Veterans Affairs Medical Center, the Department of c
Pharmacology University of California, the d Division of Endocrinology, San Francisco ... Cited by 224 - Related articles - BL Direct - All 8 versions
RBD Agostino - Statistics in Medicine, 2002 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 16 - Related articles
J Hertel, H Struthers, CB Horj, PW Hruz - Journal of Biological Chemistry, 2004 - ASBMB Human immunodeficiency virus (HIV) protease inhibitors (PIs) act as reversible noncompetitive
inhibitors of GLUT4 with binding affinities in the low micromolar range and are known to contribute
to alterations in glucose homeostasis during treatment of HIV infection. As aspartyl ... Cited by 42 - Related articles - All 5 versions
A Phillips - AIDS, 2003 - journals.lww.com In symposia highlighting results from randomized trials of antiretroviral drugs, and in discussion
sections of papers presenting such findings, a statement along the following lines is often
encountered: 'there is no randomized trial comparing regimens A and B but regimen A, in ... Cited by 17 - Related articles - BL Direct - All 4 versions
MA Noor, OP Flint, JF Maa, RA Parker - Aids, 2006 - journals.lww.com Methods: Glucose uptake was measured following insulin stimulation in differentiated human
adipocytes in the presence of ritonavir (2 μmol/l) combined with either atazanavir or lopinavir
(3-30 μmol/l). These data were examined clinically using the hyperinsulinemic ... Cited by 76 - Related articles - BL Direct - All 11 versions
