M Srinivasan, R Aalinkeel, F Song, MS Patel - Diabetes, 2003 - Am Diabetes Assoc Neonatal female rat pups that were raised artificially on a high-carbohydrate (HC) milk formula
during their suckling period developed hyperinsulinemia immediately, maintained chronic hyperinsulinemia
in the postweaning period on laboratory diet, and developed obesity in adulthood. Pups ( ... Cited by 40 - Related articles - BL Direct - All 4 versions
M Srinivasan, F Song, R Aalinkeel, MS Patel - The Journal of Nutritional …, 2001 - Elsevier Four day-old rat pups artificially raised on a high carbohydrate (HC) milk formula during their
suckling period immediately develop hyperinsulinemia which persists into adulthood despite
weaning onto lab chow on day 24. The present study investigates the molecular ... Cited by 19 - Related articles - BL Direct - All 8 versions
MS Patel, M Srinivasan - Journal of Biological Chemistry, 2002 - ASBMB The normal programmed development of a multicellular organism from the germ cell is a synchronized
series of events driven by genetic instructions acquired during conception. During the early critical
periods in life the organism also has the ability to respond to environmental situations that ... Cited by 48 - Related articles - BL Direct - All 5 versions
S Vadlamudi, SC Kalhan, MS Patel - American Journal of …, 1995 - Am Physiological Soc Vadlamudi, Satyaprasad, Satish C. Kalhan, and Mul- chand S. Patel. Persistence of metabolic
consequences in the progeny of rats fed a HC formula in their early postnatal life. Am. J.
PhysioZ. 269 (Endocrinol. Metab. 32): E731-E738, 1995.-First-generation (1-) male and ... Cited by 41 - Related articles - All 5 versions
C Junien - médecine/sciences, 2000 - ist.inserm.fr Contrairement à la grande majorité de nos gènes qui s'expriment à partir des deux allèles, les
gènes soumis à empreinte parentale ou génomique (GSE) s'expriment de façon
monoallélique, soit à partir de l'allèle paternel soit à partir de l'allèle maternel. L'étude des ... Cited by 9 - Related articles - View as HTML - All 4 versions
- ►nutrition.org JF Martin, CS Johnston, CT Han, DC Benyshek - Journal of Nutrition, 2000 - Am Soc Nutrition While there has been little success identifying the genetic bases of noninsulin-dependent
(type-2) diabetes, current epidemiological data and animal models implicate fetal undernutrition
in the development of type-2 diabetes. We examined the effects of fetal undernutrition on ... Cited by 35 - Related articles - All 5 versions
B Blondeau, I Avril, B Duchene, B Breant - Diabetologia, 2002 - Springer Proper foetal development requires an adequate ma- ternal environment. It is now well known
that mater- nal hyperglycaemia caused by gestational diabetes in- duces developmental disorders
like macrosomia, hy- perinsulinaemia and pancreatic islet hyperplasia in Cited by 34 - Related articles - BL Direct - All 5 versions
- ►physiology.org M Srinivasan, R Aalinkeel, F Song, P … - American Journal of …, 2006 - Am Physiological Soc We have previously shown that artificial rearing of newborn female rat pups on a high-carbohydrate
(HC) milk formula resulted in chronic hyperinsulinemia and adult-onset obesity (HC
phenotype) and that the maternal HC phenotype was transmitted to their progeny (2-HC ... Cited by 26 - Related articles - BL Direct - All 5 versions
N Yokomori, M Tawata, T Onaya - Diabetologia, 2002 - Springer Aims/hypothesis. The mouse leptin gene, a major hor- monal regulator of appetite and fat cell
mass, ex- presses during the differentiation of 3T3-L1 preadi- pocytes to adipocytes.To determine
if DNA methyla- tion is involved in regulating the expression of the leptin gene, we ... Cited by 16 - Related articles - BL Direct - All 2 versions
M Pembrey - Acta geneticae medicae et gemellologiae, 1996 - ncbi.nlm.nih.gov It is proposed that transgenerational modulation of gene expression might be possible, if the
metabolic response of the parent to some physiological or social stress modified imprint
setting. Transcription regulators could theoretically mediate this process. The nature of ... Cited by 38 - Related articles - BL Direct
