G Leibowitz, AI Oprescu, G Üçkaya, DJ Gross, … - Diabetes, 2003 - Am Diabetes Assoc It has recently been suggested that insulin augments its own production by a
physiologically important feed-forward autocrine loop. We studied the kinetics
of glucose-regulated proinsulin gene expression and proinsulin biosynthesis ... Cited by 18 - Related articles - BL Direct - All 4 versions
- ►endojournals.org G Leibowitz, G Uckaya, AI Oprescu, E Cerasi, … - Endocrinology, 2002 - Endocrine Soc UNDER PHYSIOLOGICAL CONDITIONS, the secretion and biosynthesis of insulin are
coordinated. Indeed, stimulation of insulin release is associated with a rapid
and sustained increase of proinsulin biosynthesis thus preventing the ... Cited by 21 - Related articles - BL Direct - All 7 versions
[CITATION] Beta cell development in mice lacking insulin and type I IGF receptors
G Leibowitz, MZ Khaldi, A Shauer, M Parnes, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1549–1559 DOI 10.1007/s00125-005-1811-6 ARTICLE
G. Leibowitz . MZ Khaldi . A. Shauer . M. Parnes . AI Oprescu . E. Cerasi . ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►jbc.org B Leibiger, K Wahlander, PO Berggren, IB … - Journal of Biological Chemistry, 2000 - ASBMB Glucose stimulation of pancreatic -cells leads to insulin secretion as well as
up-regulation of insulin biosynthesis. The acute elevation in pro-insulin levels
is thought to be exclusively because of the activation of translation of ... Cited by 44 - Related articles - BL Direct - All 3 versions
[CITATION] Molecular basis of pancreas development and fiinction
B Wicksteed, C Alarcon, I Briaud, MK Lingohr … - Journal of Biological Chemistry, 2003 - ASBMB Proinsulin biosynthesis is regulated in response to nutrients, most notably
glucose. In the short term ( 2h) this is due to increases in the translation of
pre-existing mRNA. However, prolonging glucose stimulation (24 h) also ... Cited by 62 - Related articles - BL Direct - All 4 versions
