- ►rug.nl [PDF] CH Wiegman, RHJ Bandsma, M Ouwens, FH van … - Diabetes, 2003 - Am Diabetes Assoc Type 2 diabetes in humans is associated with increased de novo lipogenesis
(DNL), increased fatty acid (FA) fluxes, decreased FA oxidation, and hepatic
steatosis. In this condition, VLDL production is increased and resistant to ... Cited by 41 - Related articles - BL Direct - All 7 versions
CH Wiegman, RHJ Bandsma, M Ouwens, FH van … - dissertations.ub.rug.nl Hepatic VLDL production in ob/ob mice ... Coen H. Wiegman 1 , Robert HJ Bandsma
1 , Margriet Ouwens 2 , Fjodor H. van der Sluijs 1 , ... Rick Havinga 1 , Theo
Boer 1 , Dirk-Jan Reijngoud 1 , Johannes A. Romijn 3 , and Folkert Kuipers 1 Related articles - View as HTML - All 5 versions
- ►diabetesjournals.org RHJ Bandsma, CH Wiegman, AW Herling, HJ … - Diabetes, 2001 - Am Diabetes Assoc Glucose-6-phosphatase (G6Pase) is a key enzyme in hepatic glucose metabolism.
Altered G6Pase activity in glycogen storage disease and diabetic states is
associated with disturbances in lipid metabolism. We studied the effects of ... Cited by 35 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org AM Brown, GF Gibbons - Arteriosclerosis, thrombosis, and vascular biology, 2001 - Am Heart Assoc Abstract—— LY 294002 (80 µmol/L), an inhibitor of phosphoinositide
3-kinase, was used to investigate the involvement of this enzyme in the
insulin-mediated regulation of very low density lipoprotein (VLDL) ... Cited by 46 - Related articles - BL Direct - All 6 versions
JN van der Veen, R Havinga, VW Bloks, AK … - Journal of lipid research, 2007 - ASBMB Page 1. Cholesterol Feeding Strongly Reduces Hepatic VLDL-Triglyceride
Production in Mice Lacking the Liver X Receptor Running title ... Cited by 13 - Related articles - All 7 versions
- ►physiology.org A Grefhorst, TH van Dijk, A Hammer, FH van … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Liver X receptor (LXR) agonists have been proposed to act as anti-diabetic
drugs. However, pharmacological LXR activation leads to severe hepatic
steatosis, a condition usually associated with insulin resistance and type ... Cited by 54 - Related articles - BL Direct - All 8 versions
- ►jlr.org [PDF] X Li, SM Grundy, SB Patel - The Journal of Lipid Research, 1997 - ASBMB Obesity in db and ob animals leads to impaired ... Xiaohua E,* Scott M.
Grundy,*3t75 and Shailesh B. Patell3*>t ... Center for Human Nutrition,*
Departments of Internal Medicine+ and Clinical Nutrition,s University of ... Cited by 28 - Related articles - BL Direct - All 6 versions
CS Au, A Wagner, T Chong, W Qiu, JD Sparks, … - Metabolism, 2004 - Elsevier Insulin is known to be a downregulator of apolipoprotein B (apoB) via the
phosphatidylinositol 3-kinase (PI3K) pathway. Akt, also known as protein kinase
B (PKB), is a serine/threonine kinase downstream target of PI3K. Recent ... Cited by 30 - Related articles - All 10 versions
- ►physiology.org A Grefhorst, J Hoekstra, TGJ Derks, DM … - American Journal of Physiology- Gastrointestinal and …, 2005 - Am Physiological Soc Accumulation of triglycerides (TG) in the liver is generally associated with
hepatic insulin resistance. We questioned whether acute hepatic steatosis
induced by pharmacological blockade of -oxidation affects hepatic insulin ... Cited by 17 - Related articles - BL Direct - All 10 versions
- ►shouxi.net C Ameen, U Edvardsson, A Ljungberg, L Asp, P … - Journal of Biological Chemistry, 2005 - ASBMB Microsomal triglyceride transfer protein (MTP) is rate-limiting in the assembly
and secretion of lipoproteins containing apolipoprotein (apo) B. Previously we
demonstrated that Wy 14,643 (Wy), a peroxisome proliferator-activated ... Cited by 62 - Related articles - All 5 versions
