CE Juge-Aubry, E Somm, V Giusti, A Pernin, R … - Diabetes, 2003 - Am Diabetes Assoc The secreted form of the interleukin-1 receptor antagonist (IL-1Ra) is an acute-phase protein
intervening in the counterregulation of inflammatory processes. We previously showed that this
cytokine antagonist is upregulated in the serum of obese patients, correlating with BMI ... Cited by 95 - Related articles - BL Direct - All 4 versions
- ►endojournals.org CA Meier, E Bobbioni, C Gabay, F … - Journal of Clinical …, 2002 - Endocrine Soc To this end, we measured serum IL-1Ra levels in 20 morbidly obese nondiabetic subjects [body
mass index (BMI), 45 ± 6 kg/m 2 ; serum leptin, 52 ± 20 ng/ml] as well as in 10 age- and sex-matched
lean controls (BMI, 22 ± 2 kg/m 2 ; serum leptin, 7 ± 4 ng/ml). Serum IL-1Ra ... Cited by 106 - Related articles - BL Direct - All 4 versions
E Somm, P Cettour-Rose, C Asensio, A Charollais, M … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 387–393 DOI 10.1007/s00125-005-0046-x ARTICLE E. Somm .
P. Cettour-Rose . C. Asensio . A. Charollais . M. Klein . C. Theander-Carrillo . CE Juge-Aubry .
J. -M. Dayer . MJH Nicklin . P. Meda . F. Rohner-Jeanrenaud . CA Meier ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►rupress.org T Matsuki, R Horai, K Sudo, Y Iwakura - Journal of Experimental …, 2003 - jem.rupress.org IL-1 is a proinflammatory cytokine that plays important roles in inflammation. However, the role
of this cytokine under physiological conditions is not known completely. In this paper, we analyzed
the role of IL-1 in maintaining body weight because IL-1 receptor antagonist–deficient (IL- ... Cited by 81 - Related articles - BL Direct - All 6 versions
- ►endojournals.org CE Juge-Aubry, E Somm, R Chicheportiche, D … - Journal of Clinical …, 2004 - Endocrine Soc We demonstrate that IL-1Ra is mainly produced by adipocytes, rather than the stromal fraction
of WAT, and that IL-1 and ß, as well as interferon-ß (IFN-ß), strongly up-regulate the expression
and secretion of IL-1Ra in WAT. Moreover, human WAT expresses the receptors and ... Cited by 45 - Related articles - BL Direct - All 4 versions
E Somm, E Henrichot, A Pernin, CE Juge-Aubry, P … - Diabetes, 2005 - Am Diabetes Assoc Interleukin (IL)-1 is a regulator of inflammation but is also implicated in the control of energy
homeostasis. Because the soluble IL-1 receptor antagonist (IL-1Ra) is markedly increased in
the serum of obese patients and is overexpressed in white adipose tissue in obesity, we ... Cited by 30 - Related articles - BL Direct - All 5 versions
GN Luheshi, JD Gardner, DA Rushforth, … - Proceedings of the …, 1999 - National Acad Sciences Leptin regulates energy balance through its actions in the brain on appetite and energy expenditure
and also shares properties with cytokines such as IL-1. We report here that leptin, injected into
rats intracerebroventricularly or peripherally, induces significant dose-dependent ... Cited by 178 - Related articles - BL Direct - All 11 versions
MC García, I Wernstedt, A Berndtsson, M Enge, M Bell, … - Diabetes, 2006 - Am Diabetes Assoc Interleukin-1 (IL-1) is a major mediator of inflammation that exerts its biological activities through
the IL-1 type I receptor (IL-1RI). The body weights of IL-1RI −/− mice of both sexes started to deviate
from those of wild-type mice at 5–6 months of age and were 20% higher at 9 months of ... Cited by 37 - Related articles - BL Direct - All 7 versions
- ►endojournals.org C Gabay, MG Dreyer, N Pellegrinelli, R … - Journal of Clinical …, 2001 - Endocrine Soc Besides its actions on the regulation of appetite, leptin has also been implicated in regulating
reproductive and immune functions. Because leptin-deficient mice are more susceptible to
lipopolysaccharide- and tumor necrosis factor- -induced shock, which is associated with ... Cited by 104 - Related articles - BL Direct - All 7 versions
CE Juge-Aubry, E Somm, A Pernin, N Alizadeh, V … - Cytokine, 2005 - Elsevier In the past decade, it became increasingly apparent that white adipose tissue (WAT) produces
various adipokines, such as leptin, adiponectin, resistin, as well as certain cytokines and
chemokines, among other tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), ... Cited by 33 - Related articles - All 4 versions
