- ►diabetesjournals.org MA Pierce, HD Chapman, CM Post, A Svetlanov … - Diabetes, 2003 - Am Diabetes Assoc Genes in the early region 3 (E3) of the adenovirus genome allow the virus to
evade host immune responses by interfering with major histocompatibility (MHC)
class I-mediated antigen presentation and tumor necrosis factor- (TNF- )- ... Cited by 18 - Related articles - BL Direct - All 5 versions
S Efrat, D Serreze, A Svetlanov, CM Post, EA … - Diabetes, 2001 - Am Diabetes Assoc The early three (E3) region of the adenovirus (Ad) encodes a number of
immunomodulatory proteins that interfere with class I major
histocompatibility–mediated antigen presentation and confer resistance to ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►nih.gov MA Pierce, A Svetlanov, MS Horwitz, DV … - The Journal of Virology, 2005 - jvi.highwire.org The incidence of type 1 diabetes (T1D) is decreased in nonobese diabetic mice
expressing the complete cassette of adenovirus early region 3 (E3)
immunomodulating genes in pancreatic ß cells. Embedded among the ... Cited by 2 - Related articles - All 9 versions
- ►nih.gov JM Friedman, MS Horwitz - Journal of virology, 2002 - Am Soc Microbiol Recombinant adenoviruses (Ads) are useful tools in gene transfer because they
are able to infect a wide variety of tissues and cell types and do not require a
replicating target cell. However, transgene expression is only transient ... Cited by 43 - Related articles - BL Direct - All 7 versions
- ►nih.gov SP Fessler, YR Chin, MS Horwitz - The Journal of Virology, 2004 - jvi.highwire.org Adenoviruses employ multiple genes to inhibit the host antiviral responses.
There is increasing evidence that these immunoregulatory genes may function
either during lytic or latent infection. Adenovirus early transcription ... Cited by 18 - Related articles - BL Direct - All 7 versions
[CITATION] Adenovirus E3-10.4/14.5 K protein complex inhibits tumor necrosis factor-induced …
SP Fessler, F Delgado-Lopez, MS Horwitz - Recent progress in multivariate approximation: 4th …, 2001 - books.google.com Mechanisms of E3 Modulation of Immune and Inflammatory Responses SP Fessler•
F. Delgado-Lopez• MS Horwitz Department of Microbiology and Immunology, Albert
Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York, NY ... Cited by 19 - Related articles - BL Direct - All 2 versions
- ►jbc.org A Hilgendorf, J Lindberg, Z Ruzsics, S Honing … - Journal of Biological Chemistry, 2003 - ASBMB The adenovirus (Ad) early transcription unit E3 encodes immunosubversive
functions. The E3 transmembrane proteins 10.4 and 14.5 form a complex that
down-regulates the epidermal growth factor receptor and apoptosis receptors ... Cited by 16 - Related articles - BL Direct - All 4 versions
HE Thomas, TWH Kay - Molecular pathology of type 1 diabetes mellitus, 2001 - books.google.com Table 1, Transgenic and knockout models in the NOD mouse Gene Effect on
insulitis Effect on diabetes Ref. IFN-y-/- Unchanged Unchanged 6 IFN-/R-/-
Unchanged Unchanged 7, 8 RIP-A-yR transgenic Unchanged Unchanged 9 iNOS-/- ... Cited by 9 - Related articles - BL Direct - All 5 versions
