P Hanifi-Moghaddam, NC Schloot, S Kappler, J Seiβler … - Diabetes, 2003 - Am Diabetes Assoc At onset of type 1 diabetes, the islet autoantibody status of patients has been reported to predict
progression of the disease. We therefore tested the hypothesis that the systemic immunoregulatory
balance, as defined by levels of circulating cytokines and chemokines, is associated with ... Cited by 41 - Related articles - BL Direct - All 4 versions
NC Schloot, P Hanifi-Moghaddam, C Goebel, … - Diabetes/Metabolism … - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 27 - Related articles - BL Direct - All 3 versions
P Zaccone, J Phillips, I Conget, A Cooke, F Nicoletti - Clinical Immunology, 2005 - Elsevier IL-18 is a type 1 pro-inflammatory cytokine with structural similarities to IL-1 and in synergy with
IL-12 stimulates IFN-γ production from T lymphocytes and polarizes development and function
of Th1 cells. Because IL-1, IFN-γ, and up-regulated Th1-mediated events are involved in ... Cited by 12 - Related articles - All 3 versions
F Nicoletti, RD Marco, G Papaccio, I … - European journal of …, 2003 - interscience.wiley.com IL-18 is a cytokine structurally and functionally related to IL-1 that, in synergy with IL-12, stimulates
the synthesis of IFN- from T lymphocytes and natural killer cells. Because IFN- plays a key pathogenic
role in the development of murine immunoinflammatory diabetes induced by multiple low ... Cited by 26 - Related articles - BL Direct - All 3 versions
S Frigerio, GA Holländer, U Zumsteg - Hormone research, 2000 - content.karger.com Background: Preclinical stages of type 1 diabetes are characterized by infiltrating T cells and
by the peri- and intra-islet accumulation of pro-inflammatory mediators, such as IFN .
Methods/Results: Using quantitative PCR we demonstrated that mRNA specific for the ... Cited by 30 - Related articles - BL Direct - All 5 versions
P Hanifi-Moghaddam, S Kappler, J Seissler, S … - Diabetic …, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 17 - Related articles - BL Direct - All 4 versions
F Nicoletti, I Conget, R Di Marco, AM Speciale, R … - Diabetologia, 2001 - Springer IL-18 is another type 1 cytokine primarily pro- duced by macrophages and closely related to the
IL- 1 family of cytokines [1]. It has been shown to play a pivotal part in the generation of type 1
cytokine re- sponses through its ability with IL-12 to up-regulate IFN-g production from ... Cited by 65 - Related articles - BL Direct - All 4 versions
NC Schloot, P Hanifi-Moghaddam, N … - Diabetic …, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org Y Oikawa, A Shimada, A Kasuga, J Morimoto … - The Journal of …, 2003 - Am Assoc Immnol IL-18 is now identified as a pleiotropic cytokine that acts as a cofactor for both Th1 and Th2 cell
development. Type 1 diabetes is considered a Th1-type autoimmune disease, and to date, the
suppressive effect of exogenous IL-18 on the development of diabetes has been reported ... Cited by 42 - Related articles - BL Direct - All 5 versions
J Bojunga, K Kusterer, M Bacher, R Kurek, KH Usadel, … - Cytokine, 2003 - Elsevier Results: MIF-mRNA expression was markedly increased in splenic lymphocytes of spontaneously
diabetic NOD mice as well as in 8-week-old NOD mice treated with cyclophosphamide compared
with 2-week-old non-diabetic NOD and healthy C57BL/6 control mice. Western blot ... Cited by 9 - Related articles - BL Direct - All 4 versions
