- ►diabetesjournals.org FM Gribble, L Williams, AK Simpson, F Reimann - Diabetes, 2003 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) secretion from intestinal l-cells is triggered by luminal
nutrients. We reported previously that glucose-triggered GLP-1 release from the l-cell model
GLUTag involves closure of ATP-sensitive K + (K ATP ) channels. We show here that ... Cited by 89 - Related articles - BL Direct - All 4 versions
F Reimann, FM Gribble - Diabetes, 2002 - Am Diabetes Assoc Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response to carbohydrate
and fat in the diet. Despite the interest in GLP-1 as an antidiabetic agent, very little is known about
the mechanism of stimulus-secretion coupling in L-cells. We investigated the ... Cited by 72 - Related articles - BL Direct - All 5 versions
- ►endojournals.org PL Brubaker, J Schloos, DJ Drucker - Endocrinology, 1998 - Endocrine Soc Glucagon-like peptide-1 (GLP-1) released from the intestine is a potent stimulator of
glucose-dependent insulin secretion. To elucidate the factors regulating GLP-1 secretion, we
have studied the enteroendocrine GLUTag cell line. GLP-1 secretion was stimulated in a ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►pnas.org A Díez-Sampedro, BA Hirayama, C … - Proceedings of the …, 2003 - National Acad Sciences We have examined the expression and function of a previously undescribed human member
(SGLT3/SLC5A4) of the sodium/glucose cotransporter gene family (SLC5) that was first identified
by the chromosome 22 genome project. The cDNA was cloned and sequenced, ... Cited by 88 - Related articles - BL Direct - All 10 versions
- ►endojournals.org RA Reimer, C Darimont, S Gremlich, V Nicolas-Metral, … - Endocrinology, 2001 - Endocrine Soc GLP-1 (glucagon-like peptide-1) is a potent insulin secretagogue released from L cells in the
intestine. The regulation of GLP-1 secretion has been described both in vivo and in vitro in several
animal species, but data from human cellular models are lacking. For this purpose, factors ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►endojournals.org Y Anini, PL Brubaker - Endocrinology, 2003 - Endocrine Soc Glucagon-like peptide 1 (GLP-1) released from distal intestinal endocrine L cells after food intake
is a potent glucose-dependent stimulant of insulin secretion. Plasma levels of GLP-1 rise rapidly
after nutrient ingestion through an indirect mechanism triggered from the proximal ... Cited by 44 - Related articles - BL Direct - All 4 versions
F Reimann, L Williams, G da Silva Xavier, GA Rutter, … - Diabetologia, 2004 - Springer Aims/hypothesis. Glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are secreted from enteroendocrine
L cells in response to nutrient ingestion. As glutamine is an important metabolic fuel for the
gut, the aim of this study was to investigate the effect of glutamine on the GLP-1-secreting ... Cited by 23 - Related articles - BL Direct - All 6 versions
DJ Drucker, T Jin, SL Asa, TA Young, PL … - Molecular …, 1994 - Endocrine Soc The gene encoding proglucagon is expressed pre- dominantly in the pancreas and
intestine. The phys- iological importance of glucagon secreted from the islets of Langerhans
has engendered considerable interest in the molecular control of proglucagon gene ... Cited by 90 - Related articles - BL Direct - All 4 versions
M Cordier-Bussat, C Bernard, F Levenez, N … - DIABETES-NEW …, 1998 - Am Diabetes Assoc Truncated glucagon-like peptide (GLP)-1 is a potent incretin. Its synthesis and secretion are modulated
by food, but the influence of individual nutrients remains to be established. The hypothesis that
protein hydrolysates (peptones) can directly regulate both GLP-1 secretion and ... Cited by 48 - Related articles - BL Direct - All 4 versions
F Reimann, M Maziarz, G Flock, AM Habib, … - The Journal of …, 2005 - Physiological Soc Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response to nutrient
ingestion. It is currently under therapeutic evaluation because it enhances insulin secretion in
type 2 diabetes. Previous studies using the GLP-1 secreting cell line GLUTag have ... Cited by 9 - Related articles - BL Direct - All 11 versions
