I Chang, S Kim, JY Kim, N Cho, YH Kim, HS … - Diabetes, 2003 - Am Diabetes Assoc Recent studies incriminating tumor necrosis factor (TNF)- as the final effector
in pancreatic ß-cell death in type 1 diabetes underscore the potential role of
TNF- -dependent NF- B activation as an important modulator of pancreatic ... Cited by 46 - Related articles - BL Direct - All 5 versions
I Chang, S Kim, JY Kim, N Cho, YH Kim, HS … - Diabetes, 2003 - Am Diabetes Assoc Recent studies incriminating tumor necrosis factor (TNF)- as the final effector
in pancreatic -cell death in type 1 diabetes underscore the potential role of
TNF- –dependent NF- B activation as an important modulator of pancreatic ... Cited by 14 - Related articles
X Han, Y Sun, S Scott, D Bleich - Diabetes, 2001 - Am Diabetes Assoc In addition to inhibiting matrix metalloproteinase-2 and matrix
metalloproteinase-9 activity, recent studies suggest that tissue inhibitor of
metalloproteinase (TIMP)-1 may inhibit apoptosis in various cell lines. To ... Cited by 45 - Related articles - BL Direct - All 6 versions
MS Baker, X Chen, XC Cao, DB Kaufman - Journal of Surgical Research, 2001 - Elsevier Background. Islet graft injury by cytokines released from inflammatory cells
(macrophages) that infiltrate the transplant site is an important mechanism of
early islet transplant dysfunction. This detrimental “cytokine effect” ... Cited by 43 - Related articles - BL Direct - All 12 versions
- ►diabetesjournals.org H Heimberg, Y Heremans, C Jobin, R Leemans, … - Diabetes, 2001 - Am Diabetes Assoc Cytokine-induced β-cell death is an important event in the pathogenesis of type
1 diabetes. The transcription factor nuclear factor-κB (NF-κB) is activated by
interleukin-1β (IL-1β), and its activity promotes the expression of ... Cited by 129 - Related articles - BL Direct - All 4 versions
N Giannoukakis, WA Rudert, M Trucco, PD … - Journal of Biological Chemistry, 2000 - ASBMB Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that inhibits β cell
function and promotes Fas-triggered apoptosis. IL-1β is thought to act early in
the initiation of the autoimmune destruction of pancreatic β cells in type ... Cited by 127 - Related articles - BL Direct - All 4 versions
- ►aacrjournals.org HS Kim, I Chang, JY Kim, KH Choi, MS Lee - Cancer research, 2005 - AACR Tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is
cytotoxic to a wide variety of transformed cells, but not to most normal cells,
implying potential therapeutic value against advanced cancer. However, ... Cited by 14 - Related articles - BL Direct - All 5 versions
[CITATION] IFNγ/TNFα synergism as the final effector in autoimmune diabetes: A key role for STAT1/IRF-1 …
H Heimberg, Y Heremans, C Jobin, R Leemans, … - Diabetes, 2001 - Am Diabetes Assoc Page 1. Inhibition of Cytokine-Induced NF- B Activation by Adenovirus-Mediated
Expression of a NF- B Super-Repressor Prevents -Cell Apoptosis ... Cited by 50 - Related articles
HE Thomas, W Irawaty, R Darwiche, TC … - Diabetes, 2004 - Am Diabetes Assoc Proinflammatory cytokines are believed to be important in pancreatic β-cell
destruction in the development of type 1 diabetes. They act by upregulation of
genes including Fas and inducible nitric oxide synthase (iNOS), which have ... Cited by 50 - Related articles - BL Direct - All 4 versions
