- ►diabetesjournals.org P Wentzel, A Ejdesjö, UJ Eriksson - Diabetes, 2003 - Am Diabetes Assoc The aim of the present study was to investigate whether diabetic embryopathy may
be associated with the inhibition of glyceraldehyde-3-phosphate dehydrogenase
(GAPDH) resulting from an excess of reactive oxygen species (ROS) in the ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Y Hiramatsu, N Sekiguchi, M Hayashi, K … - Diabetes, 2002 - Am Diabetes Assoc Activation of the diacylglycerol-protein kinase C (DAG-PKC) cascade by excess
glucose has been implicated in vascular complications of diabetes. Its
involvement in diabetic embryopathy has not been established. We examined ... Cited by 23 - Related articles - BL Direct - All 5 versions
P Wentzel, CR Wentzel, MB Gäreskog, UJ … - Birth Defects Research Part A: Clinical and Molecular … - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►bmj.com SM McKenzie, WF Doe, GD Buffinton - British Medical Journal, 1999 - gut.bmj.com Recent research has focused on the role of oxidant scavenging by
5-aminosalicylic acid (5-ASA) in the treatment of IBD. 5-ASA is able to scavenge
hypochlorite (HOCl), 9 the most potent oxidant produced by PMNs. 5-ASA also ... Cited by 16 - Related articles - BL Direct - All 6 versions
TI Chang, M Horal, SK Jain, F Wang, R Patel … - Diabetologia, 2003 - Springer Aims/hypothesis. Maternal diabetes increases oxida- tive stress in embryos.
Maternal diabetes also inhibits expression of embryonic genes, most notably,
Pax-3, which is required for neural tube closure. Here we tested the ... Cited by 54 - Related articles - BL Direct - All 4 versions
WK Kim, PE Mirkes - Birth Defects Research Part A Clinical and Molecular …, 2003 - interscience.wiley.com Previously, we showed that teratogens such as hyperthermia activate the
mitochondrial apoptotic pathway in day nine mouse embryos. Activation of this
pathway involves an initial release of cytochrome c from intermembranous ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] AT Lee, D Reis, UJ Eriksson - Diabetes, 1999 - Am Diabetes Assoc Congenital malformations affecting multiple organ sys- tems are at least three
times more common in infants of mothers with IDDM than in infants born to
nondiabetic mothers. Numerous studies have confirmed the terato- genic ... Cited by 22 - Related articles - BL Direct - All 4 versions
UJ Eriksson, P Naeser, SE Brolin - Diabetes, 1986 - Am Diabetes Assoc The effects of maternal diabetes on somatic development and activity of the
polyol pathway were investigated during early and late gestation in a rat model
for diabetic pregnancy. We studied embryo-fetal growth, mortality, and ... Cited by 24 - Related articles - All 4 versions
M Horal, Z Zhang, R Stanton, A Virkamaeki, … - Birth Defects Research Part A: Clinical and Molecular …, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 24 - Related articles - All 4 versions
P Wentzel, L Thunberg, UJ Eriksson - Diabetologia, 1997 - Springer Summary Congenital malformations are more com- mon in offspring of diabetic
mothers than offspring of non-diabetic mothers. The precise cell biological
mechanism leading to the increased incidence of con- genital malformations ... Cited by 61 - Related articles - BL Direct - All 3 versions
