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Scholar Results 1 - 10 of about 101 related to Roy: Downregulation of fibronectin overexpression reduces basement membrane thickening and.... (0.11 sec) 

Downregulation of fibronectin overexpression reduces basement membrane thickening and …

- diabetesjournals.org
S Roy, T Sato, G Paryani, R Kao - Diabetes, 2003 - Am Diabetes Assoc
Overexpression of extracellular matrix (ECM) components is closely associated
with the development of vascular basement membrane (BM) thickening, a
histological hallmark of diabetic microangiopathy. To determine whether BM ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Effect of Combined Antisense Oligonucleotides Against High-Glucose–and Diabetes- …

- uio.no [PDF] 
T Oshitari, P Polewski, M Chadda, AF Li, T … - Diabetes, 2006 - Am Diabetes Assoc
The effect of combined antisense oligonucleotides (AS-oligos) against
overexpression of extracellular matrix (ECM) components, fibronectin, laminin,
and collagen IV and on cell monolayer permeability was examined in rat ...
Cited by 17 - Related articles - BL Direct - All 7 versions

Topical instillation of ciliary neurotrophic factor inhibits retinal degeneration in …


Y Aizu, H Katayama, S Takahama, J Hu, H … - Neuroreport, 2003 - journals.lww.com
Intraocular injections of ciliary neurotrophic factor (CNTF) or intraocular
adenovirus-mediated CNTF gene transfer have been reported to inhibit retinal
alterations in inherited retinal degeneration in mice strains. To ...
Cited by 12 - Related articles - BL Direct - All 3 versions

Antisense oligonucleotides modulate high glucose-induced laminin overexpression and cell …


T Sato, G Paryani, RS Kao, AF Li, S Roy - Antisense and Nucleic Acid Drug Development, 2001 - liebertonline.com
Vascular basement membrane (BM) thickening is a prominent and characteristic
lesion of diabetic microan- giopathy. Studies suggest that increased synthesis
of laminin, a BM component, is associated with the develop- ment of ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Increased expression of basement membrane collagen in human diabetic retinopathy.

- nih.gov [PDF] 
S Roy, M Maiello, M Lorenzi - Journal of Clinical Investigation, 1994 - pubmedcentral.nih.gov
Basement membrane thickening is the most prominent and characteristic feature of
early diabetic microangiopathy. Un- known is not only the causative process but
also whether the thickening reflects increased synthesis of specific ...
Cited by 40 - Related articles - BL Direct - All 6 versions

Reduction of fibronectin expression by intravitreal administration of antisense …


S Roy, K Zhang, T Roth, S Vinogradov, RS … - Nature biotechnology, 1999 - nature.com
We have investigated whether antisense oligonucleotides delivered intravitreally
could reduce gene expression specifically in the retina. In this study,
phosphorothioate antisense oligonucleotides targeted to fibronectin ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Effect of galactose diet removal on the progression of retinal vessel changes in galactose- …

- iovs.org
PF Kador, Y Takahashi, Y Akagi, H … - Investigative ophthalmology & visual science, 2002 - ARVO
PURPOSE. Feeding dogs a diet containing 30% galactose induces experimental
galactosemia and results in the formation of diabetes-like microvascular lesions
of the retina. The appearance and progression of these retinal lesions can ...
Cited by 12 - Related articles - BL Direct - All 5 versions

[PDF] Retinal changes in Otsuka Long-Evans Tokushima Fatty rats (spontaneously diabetic rat)— …


ZY Lu, IA Bhutto, T Amemiya - Jpn J Ophthalmol, 2003 - nichigan.or.jp
Key Words: Corrosion cast, diabetic retinopathy, electron microscopy, OLETF rat,
spontaneously diabetic animal model. ... Diabetic retinopathy is one of the
most common causes of vision loss. Despite this, to date, no effec- tive ...
Cited by 6 - Related articles - All 5 versions

Increases in collagen type IV and laminin in galactose-induced retinal capillary basement …


A Das, RN Frank, NL Zhang, E Samadani - Exp Eye Res, 1990 - grande.nal.usda.gov
Record Detail. Return to previous page, Save: Title: Increases in collagen
type IV and laminin in galactose-induced retinal capillary ...
Cited by 25 - Related articles - Cached - All 3 versions

[PDF] Morphologic studies of the retina in a new diabetic model; SHR/N: Mcc-cp rat


SH Kim, YK Chu, OW Kwon, SA McCune, FH … - Yonsei Med J, 1998 - eymj.org
Soon Hyun Kim, et al. 1988). DM was induced by overloading the polyol pathway
with galactose or sucrose. However, the problems with this method were the
relatively long length of time for disease onset (24 — 36 months) and ...
Cited by 7 - Related articles - All 10 versions


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