JK Kim, JJ Fillmore, O Gavrilova, L Chao, T … - Diabetes, 2003 - Am Diabetes Assoc To determine the role of adipocytes and the tissue-specific nature in the
insulin sensitizing action of rosiglitazone, we examined the effects of 3 weeks
of rosiglitazone treatment on insulin signaling and action during ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►nih.gov L Chao, B Marcus-Samuels, MM Mason, J … - Journal of Clinical Investigation, 2000 - Am Soc Clin Investig There is uncertainty about the site(s) of action of the antidiabetic
thiazolidinediones (TZDs). These drugs are agonist ligands of the transcription
factor PPARγ, which is abundant in adipose tissue but is normally present ... Cited by 228 - Related articles - BL Direct - All 9 versions
- ►shouxi.net JK Kim, HJ Kim, SY Park, A Cederberg, R … - Diabetes, 2005 - Am Diabetes Assoc Insulin resistance plays a major role in the development of type 2 diabetes and
may be causally associated with increased intracellular fat content. Transgenic
mice with adipocyte-specific overexpression of FOXC2 (forkhead ... Cited by 14 - Related articles - All 9 versions
G Jiang, Q Dallas-Yang, Z Li, D Szalkowski, … - Diabetes, 2002 - Am Diabetes Assoc Thiazolidinediones (TZDs), agonists of peroxisome proliferator-activated
receptor-γ (PPARγ), improve insulin sensitivity in vivo, and the mechanism
remains largely unknown. In this study, we showed that, in Zucker obese ... Cited by 64 - Related articles - BL Direct - All 5 versions
- ►nih.gov JK Kim, RE Gimeno, T Higashimori, HJ Kim, H … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig 1 Department of Internal Medicine, Yale University School of Medicine, New
Haven, Connecticut, USA. 2 Millennium Pharmaceuticals Inc., Cambridge,
Massachusetts, USA. 3 Whitehead Institute for Biomedical Research, ... Cited by 112 - Related articles - BL Direct - All 11 versions
AL Hevener, W He, Y Barak, J Le, G … - Nature medicine, 2003 - salk.edu 1Department of Medicine, Division of Endocrinology and Metabolism, University of
California, San Diego, La Jolla, California 92093, USA. 2Department of Biology,
University of California, San Diego, La Jolla, California 92093, USA. ... Cited by 253 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org H Kim, M Haluzik, Z Asghar, D Yau, JW … - Diabetes, 2003 - Am Diabetes Assoc Abnormalities in insulin action are the characteristics of type 2 diabetes.
Dominant-negative muscle-specific IGF-I receptor (MKR) mice exhibit elevated
lipid levels at an early age and eventually develop type 2 diabetes. To ... Cited by 110 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org HJ Kim, T Higashimori, SY Park, H Choi, J … - Diabetes, 2004 - Am Diabetes Assoc The circulating level of the inflammatory cytokine interleukin (IL)-6 is
elevated in various insulin-resistant states including type 2 diabetes, obesity,
cancer, and HIV-associated lipodystrophy. To determine the role of IL-6 in ... Cited by 164 - Related articles - BL Direct - All 4 versions
- ►nih.gov AW Norris, L Chen, SJ Fisher, I Szanto, M … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Activation of peroxisome proliferator-activated receptor γ (PPARγ) by
thiazolidinediones (TZDs) improves insulin resistance by increasing
insulin-stimulated glucose disposal in skeletal muscle. It remains ... Cited by 207 - Related articles - BL Direct - All 6 versions
- ►physiology.org SY Park, HJ Kim, S Wang, T Higashimori, J … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Insulin resistance in skeletal muscle and heart plays a major role in the
development of type 2 diabetes and diabetic heart failure and may be causally
associated with altered lipid metabolism. Hormone-sensitive lipase (HSL) is ... Cited by 33 - Related articles - BL Direct - All 4 versions
