JA Noble, AM White, LC Lazzeroni, AM Valdes, … - Diabetes, 2003 - Am Diabetes Assoc Type 1 diabetes is an autoimmune disease with a Th1 phenotype in which
insulin-producing β-cells in the pancreas are destroyed. The T-cell–specific
transcription factor TCF7 activates genes involved in immune regulation and ... Cited by 18 - Related articles - BL Direct - All 6 versions
L Groop - Medicographia, 2005 - medicographia.org Asia, the figure is very different, only a few percent have type 1 diabetes
while the majority have type 2 diabetes. The distinction into two forms of
diabetes dates back 600 years BC when the Indian physicians Chakrata and ... Cited by 2 - Related articles - View as HTML - All 3 versions
DA Chistiakov, A Chernisheva, KV Savost'anov … - Autoimmunity, 2005 - informahealthcare.com Type 1 diabetes (T1D) is a multifactorial autoimmune disease, with strong
genetic component. Several susceptibility loci contribute to genetic
predisposition to T1D. One of these loci have been mapped to chromosome ... Cited by 3 - Related articles - All 7 versions
[CITATION] Common SNPs in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the …
- ►nih.gov CH Warden, JS Fisler - Cell metabolism, 2008 - Elsevier Animal models are invaluable resources for biomedical research, including
research on the effects of diet on metabolism and disease. Usually, great care
is taken to ensure comparable genetic backgrounds and environmental ... Cited by 5 - Related articles - All 3 versions
HQ Qu, L Marchand, R Grabs, C … - British Medical Journal, 2007 - jmg.bmj.com The interferon regulatory factor 5 gene (IRF5) has been shown to play a crucial
role in harmful immune responses by induction of proinflammatory cytokines.
Functional genetic variants associated with increasd IRF5 expression of ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►nih.gov PW Heiser, DA Cano, L Landsman, GE Kim, JG … - Gastroenterology, 2008 - Elsevier Background & Aims: β-Catenin signaling within the canonical Wnt pathway is
essential for pancreas development. However, the pathway is normally
down-regulated in the adult organ. Increased cytoplasmic and nuclear ... Cited by 7 - Related articles - All 48 versions
- ►pubget.com [PDF] E Bakhtadze, H Borg, G Stenström, P Fernlund … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1785–1794 DOI 10.1007/s00125-006-0293-5 ARTICLE
E. Bakhtadze . H. Borg . G. Stenström . P. Fernlund . HJ Arnqvist . ... Cited by 8 - Related articles - BL Direct - All 6 versions
Å Lernmark - Diabetologia, 1991 - Springer 1. Starke AAR, Heinemann L, Hohmann A, Berger M (1989) The action profiles of
human NPH insulin preparations. Diabetic Med 6:618~i22 2. Doberne L, Greenfiled
MS, Schulz B, Reaven GM (1981) En- hanced glucose utilisation during ... Cited by 8 - Related articles - All 3 versions
V Poitout, J Amyot, M Semache, B Zarrouki, D … - BBA-Molecular and Cell Biology of Lipids, 2009 - Elsevier The concept of glucolipotoxicity refers to the combined, deleterious effects of
elevated glucose, and fatty acid levels on pancreatic beta-cell function and
survival. Significant progress has been made in recent years towards a ... Cited by 8 - Related articles - BL Direct - All 4 versions
