T Bock, B Pakkenberg, K Buschard - Diabetes, 2003 - Am Diabetes Assoc It is important for our understanding of the pancreatic islets to study whether new islets are able
to form in the intact pancreas. We developed a new method to determine the total number and
the mean volume of the pancreatic islets, and we used this method to study the expansion ... Cited by 57 - Related articles - BL Direct - All 5 versions
T Tomita, V Doull, HG Pollock, D Krizsan - Pancreas, 1992 - journals.lww.com Page 1. Pancreas Vol. 7, No. 3, pp. 361-375 0 1992 Raven Press, Ltd., New York
Pancreatic Islets of Obese Hyperglycemic Mice (oblob) T. Tomita, V. Doull, "H. G.
Pollock, and tD. Krizsan Departments of Pathology, *Biochemistry ... Cited by 32 - Related articles - All 3 versions
- ►diabetesjournals.org M Skau, B Pakkenberg, K Buschard, T Bock - Diabetes, 2001 - Am Diabetes Assoc To understand the dynamics of islet population, especially during conditions with growth of the
total islet mass, it is important to have reliable estimators of parameters describing the quantitative
appearance of the islet population. We describe a stereological estimator of the volume- ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] T Bock, A Kyhnel, B Pakkenberg, K … - Journal of …, 2003 - Soc Endocrinology Studies of the postnatal growth of the -cell mass in rats have revealed some unexpected and
apparently paradoxi- cal results, the most prominent being a -cell mass plateau in the early phase
of life. We have studied the postnatal growth of the -cell mass in the domestic pig to ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org T Bock, B Pakkenberg, K Buschard - Diabetes, 2005 - Am Diabetes Assoc Key parameters of the endocrine pancreas, such as islet number, islet mass, β-cell mass, and
α-cell mass, were studied in different strains of inbred mice to investigate the impact of genetic
background on the size and structure of the endocrine pancreas. Six mice from each of ... Cited by 23 - Related articles - All 6 versions
- ►diabetesjournals.org [PDF] E Montanya, V Nacher, M Biarnes, J Soler - Diabetes, 2000 - Am Diabetes Assoc We determined the -cell replicative rate, -cell apo- ptosis, cross-sectional -cell area, and pancreatic
-cell mass throughout the entire postweaning lifespan (months 1, 3, 7, 10, 15, and 20) of Lewis
rats. -Cell replication was progressively reduced in the initial months of life but remained ... Cited by 84 - Related articles - BL Direct - All 4 versions
S Chua, S Mei Liu, Q Li, L Yang, V Thassanapaff, P … - Diabetologia, 2002 - Springer Aims. Our goal was to identify genetic variants that determine the response to insulin resistance
and hy- perglycaemia. This report documents the diabetes syn- drome of two new congenic strains
of mice generated by the transfer of the Lepr db mutation to the FVB/NJ strain and the Lep ... Cited by 28 - Related articles - BL Direct - All 4 versions
A Bulotta, L Farilla, H Hui, R Perfetti - Cell biochemistry and biophysics, 2004 - Springer Glucagon-like peptide-1 (GLP-1) is an incretin hormone capable of restoring euglycemia in
glu- cose-intolerant subjects and improving glucose control in individuals with type 2
diabetes. Whether the antidiabetic properties of GLP-1 are exclusively the result of its ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org M Teta, SY Long, LM Wartschow, MM Rankin, JA … - Diabetes, 2005 - Am Diabetes Assoc Although many signaling pathways have been shown to promote ß-cell growth, surprisingly little
is known about the normal life cycle of preexisting ß-cells or the signaling pathways required
for ß-cell survival. Adult ß-cells have been speculated to have a finite life span, with ... Cited by 99 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org M Lipsett, DT Finegood - Diabetes, 2002 - Am Diabetes Assoc Over the past few decades, we have come to appreciate that the β-cell mass is dynamic, with
a significant capacity for adaptation to changes in insulin demand (1). Increases in β-cell mass
may occur through increased β-cell replication, increased β-cell size, decreased β-cell ... Cited by 85 - Related articles - BL Direct - All 5 versions
