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Scholar Results 1 - 10 of about 101 related to Cotter: Effects of proinsulin C-peptide in experimental diabetic neuropathy. (0.11 sec) 

Effects of proinsulin C-peptide in experimental diabetic neuropathy


MA Cotter, K Ekberg, J Wahren, NE Cameron - Diabetes, 2003 - Am Diabetes Assoc
Proinsulin C-peptide treatment can partially prevent nerve dysfunction in type 1
diabetic rats and patients. This could be due to a direct action on nerve fibers
or via vascular mechanisms as C-peptide stimulates the nitric oxide (NO) ...
Cited by 51 - Related articles - BL Direct - All 4 versions

Amelioration of sensory nerve dysfunction by C-peptide in patients with type 1 diabetes


K Ekberg, T Brismar, BL Johansson, B Jonsson … - Diabetes, 2003 - Am Diabetes Assoc
Studies have demonstrated that proinsulin C-peptide stimulates the activities of
Na + ,K + -ATPase and endothelial nitric oxide synthase, both of which are
enzyme systems of importance for nerve function and known to be deficient ...
Cited by 106 - Related articles - BL Direct - All 5 versions

Effects of Proinsulin C-Peptide in Experimental Diabetic Neuropathy


S Inhibition - DIABETES, 2003 - Am Diabetes Assoc
Proinsulin C-peptide treatment can partially prevent nerve dysfunction in type 1
diabetic rats and patients. This could be due to a direct action on nerve fibers
or via vascular mechanisms as C-peptide stimulates the nitric oxide (NO) ...
Related articles

Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal …


J Shafqat, L Juntti-Berggren, Z Zhong, K … - Cellular and Molecular Life Sciences, 2002 - Springer
Abstract. Based on the findings that proinsulin C-pep- tide binds specifically
to cell membranes, we investigated the effects of C-peptide and related
molecules on the in- tracellular Ca 2+ concentration ([Ca 2+ ] i ) in human ...
Cited by 29 - Related articles - BL Direct - All 3 versions

C-peptide and diabetic neuropathy


AAF Sima - eid, 2003 - informahealthcare.com
1. Introduction 2. The natural history of diabetic polyneuropathy in Type 1 and
Type 2 diabetes 3. Pathogenetic considerations in Type 1 and Type 2 diabetic
polyneuropathy 4. The effect of C-peptide on experimental Type 1 diabetic ...
Cited by 45 - Related articles - All 4 versions

C-peptide prevents and improves chronic type I diabetic polyneuropathy in the BB/Wor rat

- kappa.ro [PDF] 
AAF Sima, W Zhang, K Sugimoto, D Henry, Z … - Diabetologia, 2001 - Springer
Diabetic polyneuropathy (DPN) occurs in Type I (in- sulin-dependent) diabetes
mellitus and Type II (non- insulin-dependent) diabetes mellitus and is believed
... C-peptide prevents and improves chronic Type I diabetic
Cited by 87 - Related articles - BL Direct - All 6 versions

Stimulation of endothelial nitric oxide synthase by proinsulin C-peptide


T Wallerath, T Kunt, T Forst, EI Closs, R … - Nitric Oxide, 2003 - Elsevier
There is increasing evidence for biological functions of human C-peptide.
Recently, we have described that proinsulin C-peptide increases nutritive
capillary blood flow and restores erythrocyte deformability in type 1 ...
Cited by 39 - Related articles - All 4 versions

Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein- …


T Kitamura, K Kimura, K Makondo, DT Furuya, … - Diabetologia, 2003 - Springer
Aims/hypothesis. Recent studies have suggested that proinsulin C-peptide
improves vascular functions, possibly through nitric oxide (NO) production. To
clarify the molecular mechanisms of vascular NO pro- duction induced by C- ...
Cited by 45 - Related articles - BL Direct - All 3 versions

C-peptide inhibits leukocyte-endothelium interaction in the microcirculation during acute …

- fasebj.org
R SCALIA, KM COYLE, BJ LEVINE, G BOOTH … - The FASEB Journal, 2000 - FASEB
C-peptide is a cleavage product that comes from processing proinsulin to insulin
that induces nitric oxide (NO) -mediated vasodilation. NO modulates
leukocyte–endothelium interaction. We hypothesized that C-peptide might ...
Cited by 46 - Related articles - BL Direct - All 3 versions

Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type …


BL Johansson, K Borg, E Fernqvist-Forbes, A … - Diabetic Medicine, 2000 - interscience.wiley.com
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Cited by 102 - Related articles - BL Direct - All 6 versions


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