- ►diabetesjournals.org L Li, T Sawamura, G Renier - Diabetes, 2003 - Am Diabetes Assoc Endothelial dysfunction is an early and key determinant of diabetic vascular complications that
is elicited at least in part by oxidized LDL (oxLDL). The recent observation that lectin-like oxLDL
receptor-1 (LOX-1) expression is increased in the vascular endothelium of diabetic rats ... Cited by 55 - Related articles - BL Direct - All 4 versions
M Chen, M Nagase, T Fujita, S Narumiya, T Masaki, … - … and Biophysical Research …, 2001 - Elsevier Diabetes mellitus accelerating atherosclerosis was associated with the enhanced glycoxidative
modification of lipoproteins. LOX-1, the endothelial oxidized LDL receptor might be involved
in the pathogenesis of diabetic atherosclerosis. In this study, we examined the vascular ... Cited by 61 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org [PDF] L Li, T Sawamura, G Renier - Circulation research, 2004 - Am Heart Assoc Abstract—Lectin-like oxidized LDL receptor-1 (LOX-1) is a newly identified receptor for oxidized
LDL that is expressed by vascular cells. LOX-1 is upregulated in aortas of diabetic rats and thus
may contribute to the pathogenesis of human diabetic atherosclerosis. In this study, we ... Cited by 57 - Related articles - BL Direct - All 5 versions
N Ouslimani, M Mahrouf, J Peynet, D Bonnefont- … - Metabolism, 2007 - Elsevier Beyond its antihyperglycemic action, the antidiabetic oral drug metformin possesses antioxidant
properties that may contribute to improve the cardiovascular deleterious effects of the diabetic
disease. We explored whether metformin could modulate the redox-sensible expression ... Cited by 17 - Related articles - All 9 versions
- ►ahajournals.org O Hofnagel, B Luechtenborg, K Stolle, S … - … , and vascular biology, 2004 - Am Heart Assoc Methods and Results— We determined by reverse-transcription polymerase chain reaction
(PCR) and Western blot analysis whether the mediators of the acute phase response in
inflammation, IL-1 , IL-1ß, and TNF- , regulate LOX-1 expression in cultured SMC, and ... Cited by 33 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org L Li, N Roumeliotis, T Sawamura, G Renier - Circulation research, 2004 - Am Heart Assoc C-reactive protein (CRP), a characteristic inflammatory marker, is a powerful predictor of cardiovascular
events. Recent data suggest that CRP may also promote atherogenesis through inducing endothelial
dysfunction. Lectin-like oxidized low-density lipoprotein (oxLDL) receptor-1 (LOX-1) is a ... Cited by 59 - Related articles - BL Direct - All 7 versions
M Nagase, K Ando, T Nagase, S Kaname, T … - … and Biophysical Research …, 2001 - Elsevier Oxidative stress has been implicated in atherosclerosis and its underlying conditions. LOX-1
is a novel endothelial receptor for oxidized low-density lipoprotein which might mediate endothelial
dysfunction and subsequent atherogenesis. In the present study, we examined LOX-1 ... Cited by 75 - Related articles - BL Direct - All 6 versions
K Hayashida, N Kume, T Murase, M Minami, D … - Circulation, 2005 - Am Heart Assoc Methods and Results— We examined serum sLOX-1 levels in 521 patients, consisting of 427
consecutive patients undergoing coronary angiography, including 80 ACS patients, 173 symptomatic
coronary heart disease patients, 122 patients with significant coronary stenosis without ... Cited by 51 - Related articles - All 12 versions
M Honjo, K Nakamura, K Yamashiro, J … - Proceedings of the …, 2003 - National Acad Sciences Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a major endothelial receptor
for oxidized low-density lipoprotein, and is assumed to play a proatherogenic role in
atherosclerosis. LOX-1 expression is induced by inflammatory cytokines as well as by ... Cited by 69 - Related articles - BL Direct - All 10 versions
- ►pnas.org M Kakutani, T Masaki, T … - Proceedings of the …, 2000 - National Acad Sciences One crucial role of endothelium is to keep the innermost surface of a blood vessel
antithrombotic. However, the endothelium also expresses prothrombotic molecules in response
to various stimuli. The balance between the antithrombotic and prothrombotic nature of ... Cited by 91 - Related articles - BL Direct - All 7 versions
