KR Short, JL Vittone, ML Bigelow, DN … - Diabetes, 2003 - Am Diabetes Assoc Insulin resistance increases and muscle oxidative capacity decreases during
aging, but lifestyle changes—especially physical activity—may reverse these
trends. Here we report the effect of a 16-week aerobic exercise program (n ... Cited by 195 - Related articles - BL Direct - All 4 versions
- ►nottingham.ac.uk [PDF] AP Russell, J Feilchenfeldt, S Schreiber, M … - Diabetes, 2003 - Am Diabetes Assoc The peroxisome proliferator-activated receptor (PPAR)-γ coactivator-1 (PGC-1)
can induce mitochondria biogenesis and has been implicated in the development of
oxidative type I muscle fibers. The PPAR isoforms α, β/δ, and γ control ... Cited by 136 - Related articles - BL Direct - All 6 versions
- ►nih.gov OE Rooyackers, DB Adey, PA Ades, KS Nair - Proceedings of the National Academy of Sciences of …, 1996 - National Acad Sciences A progressive decline in muscle performance in the rapidly expanding aging
population is causing a dramatic increase in disability and health care costs. A
decrease in muscle endurance capacity due to mitochondrial decay likely ... Cited by 186 - Related articles - BL Direct - All 8 versions
- ►nih.gov H Pilegaard, B Saltin, PD Neufer - The Journal of Physiology, 2003 - Physiological Soc Endurance exercise training induces mitochondrial biogenesis in skeletal muscle.
The peroxisome proliferator activated receptor co-activator 1α (PGC-1α) has
recently been identified as a nuclear factor critical for coordinating the ... Cited by 238 - Related articles - BL Direct - All 6 versions
- ►physiology.org J Norrbom, CJ Sundberg, H Ameln, WE Kraus, … - Journal of Applied Physiology, 2004 - Am Physiological Soc Endurance training leads to many adaptational changes in several tissues. In
skeletal muscle, fatty acid usage is enhanced and mitochondrial content is
increased. The exact molecular mechanisms regulating these functional and ... Cited by 97 - Related articles - BL Direct - All 6 versions
- ►physiology.org KR Short, JL Vittone, ML Bigelow, DN Proctor, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Aging in humans is associated with loss of lean body mass, but the causes are
incompletely defined. Lean tissue mass and function depend on continuous
rebuilding of proteins. We tested the hypotheses that whole body and mixed ... Cited by 95 - Related articles - BL Direct - All 5 versions
- ►nih.gov EV Menshikova, VB Ritov, L Fairfull, RE … - Journals of Gerontology Series A: Biological and …, 2006 - Geron Soc America Skeletal muscle mitochondria are implicated with age-related loss of function
and insulin resistance. We examined the effects of exercise on skeletal muscle
mitochondria in older (age = 67.3 ± 0.6 years) men (n = 5) and women (n = ... Cited by 45 - Related articles - BL Direct - All 4 versions
- ►physiology.org RJ Tunstall, KA Mehan, GD Wadley, GR … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc The effects of a single bout of exercise and exercise training on the expression
of genes necessary for the transport and -oxidation of fatty acids (FA),
together with the gene expression of transcription factors implicated in ... Cited by 137 - Related articles - BL Direct - All 4 versions
- ►nih.gov CS Stump, KR Short, ML Bigelow, JM Schimke … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences Mitochondria are the primary site of skeletal muscle fuel metabolism and ATP
production. Although insulin is a major regulator of fuel metabolism, its effect
on mitochondrial ATP production is not known. Here we report increases in ... Cited by 133 - Related articles - BL Direct - All 10 versions
- ►fasebj.org [PDF] AP Russell, MKC Hesselink, SK Lo, P … - The FASEB Journal, 2005 - FASEB The FASEB Journal express article 10.1096/fj.04-3168fje. Published online April
6, 2005. ... Regulation of metabolic transcriptional co-activators and ...
*Clinique Romande de Réadaptation SUVA Care, Sion, Switzerland; Cited by 59 - Related articles - All 5 versions
