- ►diabetesjournals.org JJ Wilkes, A Hevener, J Olefsky - Diabetes, 2003 - Am Diabetes Assoc We determined whether chronic endothelin-1 (ET-1) treatment could lead to in
vivo insulin resistance. Like insulin, ET-1 acutely stimulated glucose transport
in isolated soleus muscle strips of WKY rats. ET-1 pretreatment (1 h) ... Cited by 49 - Related articles - BL Direct - All 4 versions
A Ottosson-Seeberger, JM Lundberg, A … - Acta Physiologica Scandinavica, 1997 - interscience.wiley.com In states of insulin resistance, increased plasma levels of endothelin-1 and a
disturbed vascular reactivity have been reported. In order to investigate the
effects of endothelin-1 on peripheral insulin sensitivity and the ... Cited by 54 - Related articles - BL Direct - All 3 versions
- ►nih.gov K Ishibashi, T Imamura, PM Sharma, J Huang, … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig We recently reported that insulin and endothelin-1 (ET-1) can stimulate GLUT4
translocation via the heterotrimeric G protein Gαq/11 and through
PI3-kinase–mediated pathways in 3T3-L1 adipocytes. Because both hormones ... Cited by 53 - Related articles - BL Direct - All 8 versions
CC Juan, VS Fang, YJ Huang, CF Kwok, YP … - Biochemical and Biophysical Research …, 1996 - Elsevier Since endothelin-1 (ET-1) might regulate insulin secretion and glucose
metabolism, we carried out experiments to study the effect of ET-1 in conscious
rats by injecting ET-1 (0.5 or 1.0 μg/100 g body weight, ip) and examining ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►diabetes-mellitus.org [PDF] AU Teuscher, M Lerch, S Shaw, G Pacini, P … - Journal of hypertension, 1998 - journals.lww.com Cited Here...: In a randomized, single blind, crossover design, 10 lean
normotensive male subjects received either an intravenous infusion of subpressor
doses of ET-1 dissolved in polygeline or a control infusion of polygeline ... Cited by 20 - Related articles - BL Direct - All 4 versions
C Ferri, C Bellini, G Desideri, R Baldoncini, G … - Experimental and clinical endocrinology & diabetes: …, 1997 - ncbi.nlm.nih.gov We evaluated venous plasma ET-1 concentrations in 18 never-treated obese men
(body mass index 31.0 +/- 0.5 kg/m2; age 45.4 +/- 4.3 years) showing the whole
features of the above syndrome and 12 control men (age 44.1 +/- 3.6 years). ... Cited by 55 - Related articles - BL Direct
- ►diabetesjournals.org AB Strawbridge, JS Elmendorf - Diabetes, 2005 - Am Diabetes Assoc Phosphatidylinositol (PI) 4,5-bisphosphate (PIP 2 ) plays a pivotal role in
insulin-stimulated glucose transport as an important precursor to PI
3,4,5-trisphosphate (PIP 3 ) and a key regulator of actin polymerization. ... Cited by 26 - Related articles - All 6 versions
YC Lee, CC Juan, VS Fang, YP Hsu, SH Lin, … - Metabolism, 1998 - Elsevier The specificity of endothelin (ET) receptors involved in the inhibition of
insulin-stimulated glucose uptake (ISGU) in rat adipocytes was investigated.
Adipocytes were isolated from the epididymal fat pads of Sprague-Dawley ... Cited by 21 - Related articles - BL Direct - All 6 versions
- ►physiology.org G Ahlborg, J Lindstrom - Journal of Applied Physiology, 2002 - Am Physiological Soc Cardiovascular diseases are characterized by insulin resistance and elevated
endothelin (ET)-1 levels. Furthermore, ET-1 induces insulin resistance. To
elucidate this mechanism, six healthy subjects were studied during a ... Cited by 14 - Related articles - BL Direct - All 6 versions
N Berthiaume, JL Wessale, TJ Opgenorth, BA … - Metabolism, 2005 - Elsevier Atrasentan, an endothelin antagonist, would have beneficial effects on metabolic
responses in a model of insulin resistance. Zucker lean or fatty rats were
maintained either on regular (lean and fatty control, n = 12) or atrasentan- ... Cited by 7 - Related articles - All 12 versions
