QS Mi, D Ly, SE Lamhamedi-Cherradi, KV Salojin, L … - Diabetes, 2003 - Am Diabetes Assoc Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different
tissues and cells, including pancreas and lymphocytes, and can induce apoptosis in various
tumor cells but not in most normal cells. The specific roles of TRAIL in health and disease ... Cited by 50 - Related articles - BL Direct - All 4 versions
SE Lamhamedi-Cherradi, S Zheng, RM Tisch, YH … - Diabetes, 2003 - Am Diabetes Assoc Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis
of tumor cells but not most normal cells. Its roles in normal nontransformed tissues are not
clear. To explore the potential roles of TRAIL in type 1 diabetes, we examined the ... Cited by 66 - Related articles - BL Direct - All 9 versions
D Ou, D Metzger, X Wang, J Huang, P Pozzilli, A Tingle - Diabetologia, 2002 - Springer Aims/hypothesis. The aim of this study is to investi- gate whether apoptosis in human beta cells
can be related to the induction of the tumor necrosis factor- related apoptosis-inducing ligand
(TRAIL) pathway. Methods. We examined the expression of TRAIL and TRAIL receptors ... Cited by 30 - Related articles - BL Direct - All 3 versions
E Cretney, JL McQualter, N Kayagaki, H Yagita, … - Immunology and cell …, 2005 - nature.com Studies have suggested that endogenous TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L
may suppress the induction of some autoimmune diseases in mice. Here, we show that
TRAIL/Apo2L suppresses autoimmune damage in relapsing-remitting, and non-remitting ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►endojournals.org SH Wang, Z Cao, JM Wolf, M Van Antwerp, JR Baker Jr - Endocrinology, 2005 - Endocrine Soc The role of TNF-related apoptosis-inducing ligand (TRAIL) in autoimmune thyroiditis is
unclear. We used experimental autoimmune thyroiditis to clarify the contribution of TRAIL to the
development of autoimmune thyroiditis. CBA/J mice were immunized with murine ... Cited by 21 - Related articles - BL Direct - All 8 versions
- ►jimmunol.org B Hilliard, A Wilmen, C Seidel, TST Liu, R … - The Journal of …, 2001 - Am Assoc Immnol TRAIL, the TNF-related apoptosis-inducing ligand, induces apoptosis of tumor cells, but not normal
cells; the roles of TRAIL in nontransformed tissues are unknown. Using a soluble TRAIL
receptor, we examined the consequences of TRAIL blockade in an animal model of ... Cited by 133 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org JD Lunemann, S Waiczies, S Ehrlich, U … - The Journal of …, 2002 - Am Assoc Immnol TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, induces apoptosis
in susceptible cells, which can be both malignant and nontransformed. Despite homologies among
the death ligands, there are great differences between the TRAIL system on the one hand ... Cited by 73 - Related articles - BL Direct - All 5 versions
SC Cheung, DL Metzger, X Wang, J Huang, J Tai, AJ … - Pancreas, 2005 - journals.lww.com Objectives: Our previous report showed that b-cell antigen–specific CD56+ T-cells and cytokine
TRAIL mediate destruction of human pancreatic b cells in vitro. To determine whether CD56
and TRAIL are present during islet cell destruction at the onset of clinical symptoms of ... Cited by 13 - Related articles - All 3 versions
- ►aacrjournals.org Y Koga, A Matsuzaki, A Suminoe, H Hattori, T Hara - Cancer Research, 2004 - AACR To detect the novel genes expressed uniquely in neutrophils and elucidate their function, the
gene expression pattern was compared by using cDNA microarray containing 240 cytokine genes
between the neutrophils and peripheral blood mononuclear cells (PBMCs) obtained from ... Cited by 38 - Related articles - BL Direct - All 3 versions
S Ehrlich, C Infante-Duarte, B Seeger, F Zipp - Cytokine, 2003 - Elsevier In this study, we have analyzed the regulation of TRAIL surface expression and secretion in human
T cells, B cells, and monocytes in response to specific stimuli. T cells, B cells, and monocytes
were cultured in the presence of phytohemagglutinin (PHA)+interleukin (IL-2), ... Cited by 45 - Related articles - All 4 versions