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Scholar Results 1 - 10 of about 101 related to Mi: Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type.... (0.11 sec) 

Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates …


QS Mi, D Ly, SE Lamhamedi-Cherradi, KV Salojin, L … - Diabetes, 2003 - Am Diabetes Assoc
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different
tissues and cells, including pancreas and lymphocytes, and can induce apoptosis in various
tumor cells but not in most normal cells. The specific roles of TRAIL in health and disease ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Critical Roles of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand in …


SE Lamhamedi-Cherradi, S Zheng, RM Tisch, YH … - Diabetes, 2003 - Am Diabetes Assoc
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis
of tumor cells but not most normal cells. Its roles in normal nontransformed tissues are not
clear. To explore the potential roles of TRAIL in type 1 diabetes, we examined the ...
Cited by 66 - Related articles - BL Direct - All 9 versions

TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell …


D Ou, D Metzger, X Wang, J Huang, P Pozzilli, A Tingle - Diabetologia, 2002 - Springer
Aims/hypothesis. The aim of this study is to investi- gate whether apoptosis in human beta cells
can be related to the induction of the tumor necrosis factor- related apoptosis-inducing ligand
(TRAIL) pathway. Methods. We examined the expression of TRAIL and TRAIL receptors ...
Cited by 30 - Related articles - BL Direct - All 3 versions

TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental …


E Cretney, JL McQualter, N Kayagaki, H Yagita, … - Immunology and cell …, 2005 - nature.com
Studies have suggested that endogenous TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L
may suppress the induction of some autoimmune diseases in mice. Here, we show that
TRAIL/Apo2L suppresses autoimmune damage in relapsing-remitting, and non-remitting ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits …

- endojournals.org
SH Wang, Z Cao, JM Wolf, M Van Antwerp, JR Baker Jr - Endocrinology, 2005 - Endocrine Soc
The role of TNF-related apoptosis-inducing ligand (TRAIL) in autoimmune thyroiditis is
unclear. We used experimental autoimmune thyroiditis to clarify the contribution of TRAIL to the
development of autoimmune thyroiditis. CBA/J mice were immunized with murine ...
Cited by 21 - Related articles - BL Direct - All 8 versions

Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune …

- jimmunol.org
B Hilliard, A Wilmen, C Seidel, TST Liu, R … - The Journal of …, 2001 - Am Assoc Immnol
TRAIL, the TNF-related apoptosis-inducing ligand, induces apoptosis of tumor cells, but not normal
cells; the roles of TRAIL in nontransformed tissues are unknown. Using a soluble TRAIL
receptor, we examined the consequences of TRAIL blockade in an animal model of ...
Cited by 133 - Related articles - BL Direct - All 3 versions

Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto) …

- jimmunol.org
JD Lunemann, S Waiczies, S Ehrlich, U … - The Journal of …, 2002 - Am Assoc Immnol
TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, induces apoptosis
in susceptible cells, which can be both malignant and nontransformed. Despite homologies among
the death ligands, there are great differences between the TRAIL system on the one hand ...
Cited by 73 - Related articles - BL Direct - All 5 versions

Tumor necrosis factor-related apoptosis-inducing ligand and CD56 expression in …


SC Cheung, DL Metzger, X Wang, J Huang, J Tai, AJ … - Pancreas, 2005 - journals.lww.com
Objectives: Our previous report showed that b-cell antigen–specific CD56+ T-cells and cytokine
TRAIL mediate destruction of human pancreatic b cells in vitro. To determine whether CD56
and TRAIL are present during islet cell destruction at the onset of clinical symptoms of ...
Cited by 13 - Related articles - All 3 versions

Neutrophil-derived TNF-related apoptosis-inducing ligand (TRAIL): a novel …

- aacrjournals.org
Y Koga, A Matsuzaki, A Suminoe, H Hattori, T Hara - Cancer Research, 2004 - AACR
To detect the novel genes expressed uniquely in neutrophils and elucidate their function, the
gene expression pattern was compared by using cDNA microarray containing 240 cytokine genes
between the neutrophils and peripheral blood mononuclear cells (PBMCs) obtained from ...
Cited by 38 - Related articles - BL Direct - All 3 versions

Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and …


S Ehrlich, C Infante-Duarte, B Seeger, F Zipp - Cytokine, 2003 - Elsevier
In this study, we have analyzed the regulation of TRAIL surface expression and secretion in human
T cells, B cells, and monocytes in response to specific stimuli. T cells, B cells, and monocytes
were cultured in the presence of phytohemagglutinin (PHA)+interleukin (IL-2), ...
Cited by 45 - Related articles - All 4 versions


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